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Linker domain function predicts pathogenic MLH1 missense variants.
London J, Martín-López J, Yang I, Liu J, Lee JB, Fishel R. London J, et al. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2019215118. doi: 10.1073/pnas.2019215118. Proc Natl Acad Sci U S A. 2021. PMID: 33619096 Free PMC article.
Dynamic control of strand excision during human DNA mismatch repair.
Jeon Y, Kim D, Martín-López JV, Lee R, Oh J, Hanne J, Fishel R, Lee JB. Jeon Y, et al. Among authors: martin lopez jv. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3281-6. doi: 10.1073/pnas.1523748113. Epub 2016 Mar 7. Proc Natl Acad Sci U S A. 2016. PMID: 26951673 Free PMC article.
MutS homolog sliding clamps shield the DNA from binding proteins.
Hanne J, Britton BM, Park J, Liu J, Martín-López J, Jones N, Schoffner M, Klajner P, Bundschuh R, Lee JB, Fishel R. Hanne J, et al. J Biol Chem. 2018 Sep 14;293(37):14285-14294. doi: 10.1074/jbc.RA118.002264. Epub 2018 Aug 2. J Biol Chem. 2018. PMID: 30072380 Free PMC article.
The hMSH2(M688R) Lynch syndrome mutation may function as a dominant negative.
Martín-López JV, Barrios Y, Medina-Arana V, Andújar M, Lee S, Gu L, Li GM, Rüschoff J, Salido E, Fishel R. Martín-López JV, et al. Carcinogenesis. 2012 Sep;33(9):1647-54. doi: 10.1093/carcin/bgs199. Epub 2012 Jun 27. Carcinogenesis. 2012. PMID: 22739024 Free PMC article.
Mutation of TGFβ-RII eliminates NSAID cancer chemoprevention.
Martín-López J, Gasparini P, Coombes K, Croce CM, Boivin GP, Fishel R. Martín-López J, et al. Oncotarget. 2017 Dec 31;9(16):12554-12561. doi: 10.18632/oncotarget.23792. eCollection 2018 Feb 27. Oncotarget. 2017. PMID: 29560090 Free PMC article.
New founding mutation in MSH2 associated with hereditary nonpolyposis colorectal cancer syndrome on the Island of Tenerife.
Medina-Arana V, Barrios Y, Fernández-Peralta A, Herrera M, Chinea N, Lorenzo N, Jiménez A, Martín-López JV, González-Hermoso F, Salido E, González-Aguilera JJ. Medina-Arana V, et al. Among authors: martin lopez jv. Cancer Lett. 2006 Dec 8;244(2):268-73. doi: 10.1016/j.canlet.2005.12.033. Epub 2006 Feb 24. Cancer Lett. 2006. PMID: 16500024
14 results