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RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.
Akula N, Barb J, Jiang X, Wendland JR, Choi KH, Sen SK, Hou L, Chen DT, Laje G, Johnson K, Lipska BK, Kleinman JE, Corrada-Bravo H, Detera-Wadleigh S, Munson PJ, McMahon FJ. Akula N, et al. Among authors: laje g. Mol Psychiatry. 2014 Nov;19(11):1179-85. doi: 10.1038/mp.2013.170. Epub 2014 Jan 7. Mol Psychiatry. 2014. PMID: 24393808 Free PMC article.
Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression.
Hu XZ, Rush AJ, Charney D, Wilson AF, Sorant AJ, Papanicolaou GJ, Fava M, Trivedi MH, Wisniewski SR, Laje G, Paddock S, McMahon FJ, Manji H, Lipsky RH. Hu XZ, et al. Among authors: laje g. Arch Gen Psychiatry. 2007 Jul;64(7):783-92. doi: 10.1001/archpsyc.64.7.783. Arch Gen Psychiatry. 2007. PMID: 17606812 Clinical Trial.
The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort.
Lekman M, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ, Paddock S. Lekman M, et al. Among authors: laje g. Biol Psychiatry. 2008 Jun 15;63(12):1103-10. doi: 10.1016/j.biopsych.2007.10.026. Epub 2008 Jan 11. Biol Psychiatry. 2008. PMID: 18191112 Free PMC article. Clinical Trial.
67 results