Clark RL - Search Results

1

Dihydroartemisinin (DHA) treatment causes an arrest of cell division and apoptosis in rat embryonic erythroblasts in whole embryo culture.

Posobiec LM, Clark RL, Bushdid PB, Laffan SB, Wang KF, White TE. Posobiec LM, et al. Among authors: clark rl. Birth Defects Res B Dev Reprod Toxicol. 2013 Dec;98(6):445-58. doi: 10.1002/bdrb.21088. Epub 2014 Jan 3. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 24391093

2

Developmental toxicity of artesunate and an artesunate combination in the rat and rabbit.

Clark RL, White TE, A Clode S, Gaunt I, Winstanley P, Ward SA. Clark RL, et al. Birth Defects Res B Dev Reprod Toxicol. 2004 Dec;71(6):380-94. doi: 10.1002/bdrb.20027. Birth Defects Res B Dev Reprod Toxicol. 2004. PMID: 15617018

3

Artesunate-induced depletion of embryonic erythroblasts precedes embryolethality and teratogenicity in vivo.

White TE, Bushdid PB, Ritter S, Laffan SB, Clark RL. White TE, et al. Among authors: clark rl. Birth Defects Res B Dev Reprod Toxicol. 2006 Oct;77(5):413-29. doi: 10.1002/bdrb.20092. Birth Defects Res B Dev Reprod Toxicol. 2006. PMID: 17066416

4

Sensitive periods for developmental toxicity of orally administered artesunate in the rat.

White TE, Clark RL. White TE, et al. Among authors: clark rl. Birth Defects Res B Dev Reprod Toxicol. 2008 Aug;83(4):407-17. doi: 10.1002/bdrb.20157. Birth Defects Res B Dev Reprod Toxicol. 2008. PMID: 18615704

5

Artesunate: developmental toxicity and toxicokinetics in monkeys.

Clark RL, Arima A, Makori N, Nakata Y, Bernard F, Gristwood W, Harrell A, White TE, Wier PJ. Clark RL, et al. Birth Defects Res B Dev Reprod Toxicol. 2008 Aug;83(4):418-34. doi: 10.1002/bdrb.20163. Birth Defects Res B Dev Reprod Toxicol. 2008. PMID: 18702116

6

Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count.

Clark RL, Lerman SA, Cox EM, Gristwood WE, White TE. Clark RL, et al. Birth Defects Res B Dev Reprod Toxicol. 2008 Aug;83(4):397-406. doi: 10.1002/bdrb.20165. Birth Defects Res B Dev Reprod Toxicol. 2008. PMID: 18702118

7

The potential role for corticosterone in the induction of cleft palate in mice after treatment with a selective NK-1 receptor antagonist, casopitant (GW679769B).

Ziejewski MK, Solomon HM, Stanislaus D, Clark RL, White TE, Apostoli AR. Ziejewski MK, et al. Among authors: clark rl. Birth Defects Res B Dev Reprod Toxicol. 2012 Feb;95(1):54-62. doi: 10.1002/bdrb.20341. Epub 2011 Nov 29. Birth Defects Res B Dev Reprod Toxicol. 2012. PMID: 22127931

8

Localization of artesunate and its derivatives in the pregnant rat and fetus following oral administration and relationship to developmental toxicity.

Clark RL, Gristwood WE, Lewsley R, Wilson R, Harrell AW. Clark RL, et al. Birth Defects Res B Dev Reprod Toxicol. 2010 Oct;89(5):364-75. doi: 10.1002/bdrb.20256. Birth Defects Res B Dev Reprod Toxicol. 2010. PMID: 20717981

9

Selection of normalizer genes in conducting relative gene expression analysis of embryos.

Zhang QJ, Chadderton A, Clark RL, Augustine-Rauch KA. Zhang QJ, et al. Among authors: clark rl. Birth Defects Res A Clin Mol Teratol. 2003 Aug;67(8):533-44. doi: 10.1002/bdra.10075. Birth Defects Res A Clin Mol Teratol. 2003. PMID: 14632301

10

Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate.

Clark RL, Edwards TL, Longo M, Kinney J, Walker DK, Rhodes J, Clode SA, Rückle T, Wells T, Andenmatten N, Huber AC. Clark RL, et al. Birth Defects Res. 2018 Apr 17;110(7):553-578. doi: 10.1002/bdr2.1170. Epub 2017 Nov 28. Birth Defects Res. 2018. PMID: 29193867

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