Malek S - Search Results

1

Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

Cao F, Townsend EC, Karatas H, Xu J, Li L, Lee S, Liu L, Chen Y, Ouillette P, Zhu J, Hess JL, Atadja P, Lei M, Qin ZS, Malek S, Wang S, Dou Y. Cao F, et al. Among authors: malek s. Mol Cell. 2014 Jan 23;53(2):247-61. doi: 10.1016/j.molcel.2013.12.001. Epub 2014 Jan 2. Mol Cell. 2014. PMID: 24389101 Free PMC article.

2

Comprehensive analysis of copy number and allele status identifies multiple chromosome defects underlying follicular lymphoma pathogenesis.

Ross CW, Ouillette PD, Saddler CM, Shedden KA, Malek SN. Ross CW, et al. Clin Cancer Res. 2007 Aug 15;13(16):4777-85. doi: 10.1158/1078-0432.CCR-07-0456. Clin Cancer Res. 2007. PMID: 17699855

3

Comprehensive biomarker and genomic analysis identifies p53 status as the major determinant of response to MDM2 inhibitors in chronic lymphocytic leukemia.

Saddler C, Ouillette P, Kujawski L, Shangary S, Talpaz M, Kaminski M, Erba H, Shedden K, Wang S, Malek SN. Saddler C, et al. Among authors: malek sn. Blood. 2008 Feb 1;111(3):1584-93. doi: 10.1182/blood-2007-09-112698. Epub 2007 Oct 30. Blood. 2008. PMID: 17971485 Free article.

4

Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14.

Ouillette P, Erba H, Kujawski L, Kaminski M, Shedden K, Malek SN. Ouillette P, et al. Cancer Res. 2008 Feb 15;68(4):1012-21. doi: 10.1158/0008-5472.CAN-07-3105. Cancer Res. 2008. PMID: 18281475

5

The pre-clinical development of MDM2 inhibitors in chronic lymphocytic leukemia uncovers a central role for p53 status in sensitivity to MDM2 inhibitor-mediated apoptosis.

Bixby D, Kujawski L, Wang S, Malek SN. Bixby D, et al. Among authors: malek sn. Cell Cycle. 2008 Apr 15;7(8):971-9. doi: 10.4161/cc.7.8.5754. Epub 2008 Feb 19. Cell Cycle. 2008. PMID: 18414049 Review.

6

Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia.

Kujawski L, Ouillette P, Erba H, Saddler C, Jakubowiak A, Kaminski M, Shedden K, Malek SN. Kujawski L, et al. Blood. 2008 Sep 1;112(5):1993-2003. doi: 10.1182/blood-2007-07-099432. Epub 2008 Apr 24. Blood. 2008. PMID: 18436738 Free PMC article.

7

Aggressive chronic lymphocytic leukemia with elevated genomic complexity is associated with multiple gene defects in the response to DNA double-strand breaks.

Ouillette P, Fossum S, Parkin B, Ding L, Bockenstedt P, Al-Zoubi A, Shedden K, Malek SN. Ouillette P, et al. Among authors: malek sn. Clin Cancer Res. 2010 Feb 1;16(3):835-47. doi: 10.1158/1078-0432.CCR-09-2534. Epub 2010 Jan 19. Clin Cancer Res. 2010. PMID: 20086003 Free PMC article.

8

Multiple distinct molecular mechanisms influence sensitivity and resistance to MDM2 inhibitors in adult acute myelogenous leukemia.

Long J, Parkin B, Ouillette P, Bixby D, Shedden K, Erba H, Wang S, Malek SN. Long J, et al. Among authors: malek sn. Blood. 2010 Jul 8;116(1):71-80. doi: 10.1182/blood-2010-01-261628. Epub 2010 Apr 19. Blood. 2010. PMID: 20404136 Free PMC article.

9

NF1 inactivation in adult acute myelogenous leukemia.

Parkin B, Ouillette P, Wang Y, Liu Y, Wright W, Roulston D, Purkayastha A, Dressel A, Karp J, Bockenstedt P, Al-Zoubi A, Talpaz M, Kujawski L, Liu Y, Shedden K, Shakhan S, Li C, Erba H, Malek SN. Parkin B, et al. Among authors: malek sn. Clin Cancer Res. 2010 Aug 15;16(16):4135-47. doi: 10.1158/1078-0432.CCR-09-2639. Epub 2010 May 26. Clin Cancer Res. 2010. PMID: 20505189 Free PMC article.

10

Acquired genomic copy number aberrations and survival in adult acute myelogenous leukemia.

Parkin B, Erba H, Ouillette P, Roulston D, Purkayastha A, Karp J, Talpaz M, Kujawski L, Shakhan S, Li C, Shedden K, Malek SN. Parkin B, et al. Among authors: malek sn. Blood. 2010 Dec 2;116(23):4958-67. doi: 10.1182/blood-2010-01-266999. Epub 2010 Aug 20. Blood. 2010. PMID: 20729466 Free PMC article.

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