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Page 1
Aprepitant is a novel, selective activator of the K2P channel TRAAK.
McCoull D, Veale EL, Walsh Y, Byrom L, Avkiran T, Large JM, Vaitone E, Gaffey F, Jerman J, Mathie A, Wright PD. McCoull D, et al. Among authors: jerman j. Biochem Biophys Res Commun. 2022 Jan 15;588:41-46. doi: 10.1016/j.bbrc.2021.12.031. Epub 2021 Dec 14. Biochem Biophys Res Commun. 2022. PMID: 34942533 Free article.
The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy.
McCloskey C, Rada C, Bailey E, McCavera S, van den Berg HA, Atia J, Rand DA, Shmygol A, Chan YW, Quenby S, Brosens JJ, Vatish M, Zhang J, Denton JS, Taggart MJ, Kettleborough C, Tickle D, Jerman J, Wright P, Dale T, Kanumilli S, Trezise DJ, Thornton S, Brown P, Catalano R, Lin N, England SK, Blanks AM. McCloskey C, et al. Among authors: jerman j. EMBO Mol Med. 2014 Sep;6(9):1161-74. doi: 10.15252/emmm.201403944. EMBO Mol Med. 2014. PMID: 25056913 Free PMC article.
Discovery of small molecule antagonists of TRPV1.
Rami HK, Thompson M, Wyman P, Jerman JC, Egerton J, Brough S, Stevens AJ, Randall AD, Smart D, Gunthorpe MJ, Davis JB. Rami HK, et al. Among authors: jerman jc. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3631-4. doi: 10.1016/j.bmcl.2004.05.028. Bioorg Med Chem Lett. 2004. PMID: 15203132
91 results