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A causal role for TRESK loss of function in migraine mechanisms.
Pettingill P, Weir GA, Wei T, Wu Y, Flower G, Lalic T, Handel A, Duggal G, Chintawar S, Cheung J, Arunasalam K, Couper E, Haupt LM, Griffiths LR, Bassett A, Cowley SA, Cader MZ. Pettingill P, et al. Among authors: cader mz. Brain. 2019 Dec 1;142(12):3852-3867. doi: 10.1093/brain/awz342. Brain. 2019. PMID: 31742594 Free PMC article.
A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura.
Lafrenière RG, Cader MZ, Poulin JF, Andres-Enguix I, Simoneau M, Gupta N, Boisvert K, Lafrenière F, McLaughlan S, Dubé MP, Marcinkiewicz MM, Ramagopalan S, Ansorge O, Brais B, Sequeiros J, Pereira-Monteiro JM, Griffiths LR, Tucker SJ, Ebers G, Rouleau GA. Lafrenière RG, et al. Among authors: cader mz. Nat Med. 2010 Oct;16(10):1157-60. doi: 10.1038/nm.2216. Epub 2010 Sep 26. Nat Med. 2010. PMID: 20871611
Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics.
Handel AE, Chintawar S, Lalic T, Whiteley E, Vowles J, Giustacchini A, Argoud K, Sopp P, Nakanishi M, Bowden R, Cowley S, Newey S, Akerman C, Ponting CP, Cader MZ. Handel AE, et al. Among authors: cader mz. Hum Mol Genet. 2016 Mar 1;25(5):989-1000. doi: 10.1093/hmg/ddv637. Epub 2016 Jan 5. Hum Mol Genet. 2016. PMID: 26740550 Free PMC article.
New directions in migraine.
Weir GA, Cader MZ. Weir GA, et al. Among authors: cader mz. BMC Med. 2011 Oct 25;9:116. doi: 10.1186/1741-7015-9-116. BMC Med. 2011. PMID: 22027350 Free PMC article. Review.
Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers.
Jarosz-Griffiths HH, Corbett NJ, Rowland HA, Fisher K, Jones AC, Baron J, Howell GJ, Cowley SA, Chintawar S, Cader MZ, Kellett KAB, Hooper NM. Jarosz-Griffiths HH, et al. Among authors: cader mz. J Biol Chem. 2019 Apr 26;294(17):7085-7097. doi: 10.1074/jbc.RA118.005364. Epub 2019 Mar 14. J Biol Chem. 2019. PMID: 30872401 Free PMC article.
Investigation of CACNA1I Cav3.3 Dysfunction in Hemiplegic Migraine.
Maksemous N, Blayney CD, Sutherland HG, Smith RA, Lea RA, Tran KN, Ibrahim O, McArthur JR, Haupt LM, Cader MZ, Finol-Urdaneta RK, Adams DJ, Griffiths LR. Maksemous N, et al. Among authors: cader mz. Front Mol Neurosci. 2022 Jul 19;15:892820. doi: 10.3389/fnmol.2022.892820. eCollection 2022. Front Mol Neurosci. 2022. PMID: 35928792 Free PMC article.
85 results