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Page 1
Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein.
Dening Y, Straßl T, Ruf V, Dirscherl P, Chovsepian A, Stievenard A, Khairnar A, Schmidt F, Giesert F, Herms J, Levin J, Dieterich M, Falkai P, Weisenhorn DV, Wurst W, Giese A, Pan-Montojo F. Dening Y, et al. Among authors: giesert f. Sci Rep. 2022 Dec 19;12(1):21951. doi: 10.1038/s41598-022-25790-2. Sci Rep. 2022. PMID: 36535974 Free PMC article.
Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.
Gruber C, Krautner L, Bergant V, Grass V, Ma Z, Rheinemann L, Krus A, Reinhardt F, Mazneykova L, Rocha-Hasler M, Truong DJ, Westmeyer GG, Pichlmair A, Ebert G, Giesert F, Wurst W. Gruber C, et al. Among authors: giesert f. Cell Discov. 2024 Apr 12;10(1):42. doi: 10.1038/s41421-024-00672-1. Cell Discov. 2024. PMID: 38609360 Free PMC article. No abstract available.
A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.
Giusti SA, Pino NS, Pannunzio C, Ogando MB, Armando NG, Garrett L, Zimprich A, Becker L, Gimeno ML, Lukin J, Merino FL, Pardi MB, Pedroncini O, Di Mauro GC, Durner VG, Fuchs H, de Angelis MH, Patop IL, Turck CW, Deussing JM, Vogt Weisenhorn DM, Jahn O, Kadener S, Hölter SM, Brose N, Giesert F, Wurst W, Marin-Burgin A, Refojo D. Giusti SA, et al. Among authors: giesert f. Sci Adv. 2024 May 24;10(21):eadj8769. doi: 10.1126/sciadv.adj8769. Epub 2024 May 24. Sci Adv. 2024. PMID: 38787942 Free PMC article.
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.
Xu M, Ito-Kureha T, Kang HS, Chernev A, Raj T, Hoefig KP, Hohn C, Giesert F, Wang Y, Pan W, Ziętara N, Straub T, Feederle R, Daniel C, Adler B, König J, Feske S, Tsokos GC, Wurst W, Urlaub H, Sattler M, Kisielow J, Wulczyn FG, Łyszkiewicz M, Heissmeyer V. Xu M, et al. Among authors: giesert f. Nat Commun. 2024 Mar 11;15(1):2194. doi: 10.1038/s41467-024-46371-z. Nat Commun. 2024. PMID: 38467629 Free PMC article.
A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.
Schmidt S, Stautner C, Vu DT, Heinz A, Regensburger M, Karayel O, Trümbach D, Artati A, Kaltenhäuser S, Nassef MZ, Hembach S, Steinert L, Winner B, Jürgen W, Jastroch M, Luecken MD, Theis FJ, Westmeyer GG, Adamski J, Mann M, Hiller K, Giesert F, Vogt Weisenhorn DM, Wurst W. Schmidt S, et al. Among authors: giesert f. Nat Commun. 2023 Nov 23;14(1):7674. doi: 10.1038/s41467-023-42862-7. Nat Commun. 2023. PMID: 37996418 Free PMC article.
Correction to "The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression".
Xu M, Ito-Kureha T, Kang HS, Chernev A, Raj T, Hoefig KP, Hohn C, Giesert F, Wang Y, Pan W, Ziętara N, Straub T, Feederle R, Daniel C, Adler B, König J, Feske S, Tsokos GC, Wurst W, Urlaub H, Sattler M, Kisielow J, Wulczyn FG, Łyszkiewicz M, Heissmeyer V. Xu M, et al. Among authors: giesert f. Nat Commun. 2024 Aug 5;15(1):6632. doi: 10.1038/s41467-024-50610-8. Nat Commun. 2024. PMID: 39103338 Free PMC article. No abstract available.
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.
Chee JM, Lanoue L, Clary D, Higgins K, Bower L, Flenniken A, Guo R, Adams DJ, Bosch F, Braun RE, Brown SDM, Chin HG, Dickinson ME, Hsu CW, Dobbie M, Gao X, Galande S, Grobler A, Heaney JD, Herault Y, de Angelis MH, Mammano F, Nutter LMJ, Parkinson H, Qin C, Shiroishi T, Sedlacek R, Seong JK, Xu Y; International Mouse Phenotyping Consortium; Brooks B, McKerlie C, Lloyd KCK, Westerberg H, Moshiri A. Chee JM, et al. BMC Biol. 2023 Feb 3;21(1):22. doi: 10.1186/s12915-022-01475-0. BMC Biol. 2023. PMID: 36737727 Free PMC article.
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool.
Piccoli G, Condliffe SB, Bauer M, Giesert F, Boldt K, De Astis S, Meixner A, Sarioglu H, Vogt-Weisenhorn DM, Wurst W, Gloeckner CJ, Matteoli M, Sala C, Ueffing M. Piccoli G, et al. Among authors: giesert f. J Neurosci. 2011 Feb 9;31(6):2225-37. doi: 10.1523/JNEUROSCI.3730-10.2011. J Neurosci. 2011. PMID: 21307259 Free PMC article.
48 results