Flora DB - Search Results

1

Irreversible sortase A-mediated ligation driven by diketopiperazine formation.

Liu F, Luo EY, Flora DB, Mezo AR. Liu F, et al. Among authors: flora db. J Org Chem. 2014 Jan 17;79(2):487-92. doi: 10.1021/jo4024914. Epub 2014 Jan 6. J Org Chem. 2014. PMID: 24378034

2

Concise synthetic routes to human insulin.

Liu F, Luo EY, Flora DB, Mayer JP. Liu F, et al. Among authors: flora db. Org Lett. 2013 Feb 15;15(4):960-3. doi: 10.1021/ol400149j. Epub 2013 Feb 7. Org Lett. 2013. PMID: 23391097

3

A synthetic route to human insulin using isoacyl peptides.

Liu F, Luo EY, Flora DB, Mezo AR. Liu F, et al. Among authors: flora db. Angew Chem Int Ed Engl. 2014 Apr 7;53(15):3983-7. doi: 10.1002/anie.201310735. Epub 2014 Mar 11. Angew Chem Int Ed Engl. 2014. PMID: 24615765

4

Detection and control of aspartimide formation in the synthesis of cyclic peptides.

Flora D, Mo H, Mayer JP, Khan MA, Yan LZ. Flora D, et al. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1065-8. doi: 10.1016/j.bmcl.2004.12.025. Bioorg Med Chem Lett. 2005. PMID: 15686913

5

Discovery of a beta-MSH-derived MC-4R selective agonist.

Mayer JP, Hsiung HM, Flora DB, Edwards P, Smith DP, Zhang XY, Gadski RA, Heiman ML, Hertel JL, Emmerson PJ, Husain S, O'brien TP, Kahl SD, Smiley DL, Zhang L, Dimarchi RD, Yan LZ. Mayer JP, et al. Among authors: flora db. J Med Chem. 2005 May 5;48(9):3095-8. doi: 10.1021/jm0501432. J Med Chem. 2005. PMID: 15857110

6

Structure-activity relationships of beta-MSH derived melanocortin-4 receptor peptide agonists.

Yan LZ, Hsiung HM, Heiman ML, Gadski RA, Emmerson PJ, Hertel J, Flora D, Edwards P, Smiley D, Zhang L, Husain S, Kahl SD, DiMarchi RD, Mayer JP. Yan LZ, et al. Curr Top Med Chem. 2007;7(11):1052-67. doi: 10.2174/156802607780906591. Curr Top Med Chem. 2007. PMID: 17584126 Review.

7

Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold.

Yan LZ, Flora D, Edwards P, Smiley DL, Emmerson PJ, Hsiung HM, Gadski R, Hertel J, Heiman ML, Husain S, O'Brien TP, Kahl SD, Zhang L, Dimarchi RD, Mayer JP. Yan LZ, et al. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4611-4. doi: 10.1016/j.bmcl.2005.06.081. Bioorg Med Chem Lett. 2005. PMID: 16105738

8

Discovery of potent, cyclic calcitonin gene-related peptide receptor antagonists.

Yan LZ, Johnson KW, Rothstein E, Flora D, Edwards P, Li B, Li J, Lynch R, Vaughn R, Clemens-Smith A, McCarty D, Chow C, McKnight KL, Lu J, Nisenbaum ES, Mayer JP. Yan LZ, et al. J Pept Sci. 2011 May;17(5):383-6. doi: 10.1002/psc.1358. Epub 2011 Mar 15. J Pept Sci. 2011. PMID: 21412957

9

Hybrid insulin cocrystals for controlled release delivery.

Brader ML, Sukumar M, Pekar AH, McClellan DS, Chance RE, Flora DB, Cox AL, Irwin L, Myers SR. Brader ML, et al. Among authors: flora db. Nat Biotechnol. 2002 Aug;20(8):800-4. doi: 10.1038/nbt722. Epub 2002 Jul 22. Nat Biotechnol. 2002. PMID: 12134168

10

Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor.

Slieker LJ, Brooke GS, DiMarchi RD, Flora DB, Green LK, Hoffmann JA, Long HB, Fan L, Shields JE, Sundell KL, Surface PL, Chance RE. Slieker LJ, et al. Among authors: flora db. Diabetologia. 1997 Jul;40 Suppl 2:S54-61. doi: 10.1007/s001250051402. Diabetologia. 1997. PMID: 9248702

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