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Page 1
Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (-)-[(18)F]Flubatine in humans.
Patt M, Becker GA, Grossmann U, Habermann B, Schildan A, Wilke S, Deuther-Conrad W, Graef S, Fischer S, Smits R, Hoepping A, Wagenknecht G, Steinbach J, Gertz HJ, Hesse S, Schönknecht P, Brust P, Sabri O. Patt M, et al. Among authors: smits r. Nucl Med Biol. 2014 Jul;41(6):489-94. doi: 10.1016/j.nucmedbio.2014.03.018. Epub 2014 Mar 29. Nucl Med Biol. 2014. PMID: 24768146
Internal dose assessment of (-)-18F-flubatine, comparing animal model datasets of mice and piglets with first-in-human results.
Sattler B, Kranz M, Starke A, Wilke S, Donat CK, Deuther-Conrad W, Patt M, Schildan A, Patt J, Smits R, Hoepping A, Schoenknecht P, Steinbach J, Brust P, Sabri O. Sattler B, et al. Among authors: smits r. J Nucl Med. 2014 Nov;55(11):1885-92. doi: 10.2967/jnumed.114.137059. Epub 2014 Oct 6. J Nucl Med. 2014. PMID: 25286922 Free article.
First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (-)-[(18)F]Flubatine.
Sabri O, Becker GA, Meyer PM, Hesse S, Wilke S, Graef S, Patt M, Luthardt J, Wagenknecht G, Hoepping A, Smits R, Franke A, Sattler B, Habermann B, Neuhaus P, Fischer S, Tiepolt S, Deuther-Conrad W, Barthel H, Schönknecht P, Brust P. Sabri O, et al. Among authors: smits r. Neuroimage. 2015 Sep;118:199-208. doi: 10.1016/j.neuroimage.2015.05.065. Epub 2015 May 30. Neuroimage. 2015. PMID: 26037057
Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.
Wenzel B, Mollitor J, Deuther-Conrad W, Dukic-Stefanovic S, Kranz M, Vraka C, Teodoro R, Günther R, Donat CK, Ludwig FA, Fischer S, Smits R, Wadsak W, Mitterhauser M, Steinbach J, Hoepping A, Brust P. Wenzel B, et al. Among authors: smits r. J Med Chem. 2016 Mar 10;59(5):1800-17. doi: 10.1021/acs.jmedchem.5b01080. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26796795
LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors.
Ludwig FA, Smits R, Fischer S, Donat CK, Hoepping A, Brust P, Steinbach J. Ludwig FA, et al. Among authors: smits r. Molecules. 2016 Sep 8;21(9):1200. doi: 10.3390/molecules21091200. Molecules. 2016. PMID: 27617996 Free PMC article.
Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia.
Sabri O, Meyer PM, Gräf S, Hesse S, Wilke S, Becker GA, Rullmann M, Patt M, Luthardt J, Wagenknecht G, Hoepping A, Smits R, Franke A, Sattler B, Tiepolt S, Fischer S, Deuther-Conrad W, Hegerl U, Barthel H, Schönknecht P, Brust P. Sabri O, et al. Among authors: smits r. Brain. 2018 Jun 1;141(6):1840-1854. doi: 10.1093/brain/awy099. Brain. 2018. PMID: 29672680 Free PMC article.
294 results