Kong DX - Search Results

1

Design potential selective inhibitors for treating cancer by targeting the Src homology 2 (SH2) domain-containing phosphatase 2 (Shp2) with core hopping approach.

Duan YQ, Ma Y, Wang XJ, Jin YY, Wang RL, Dong WL, Xu WR, Kong DX, Wang SQ. Duan YQ, et al. Among authors: kong dx. Protein Pept Lett. 2014 Jun;21(6):556-63. doi: 10.2174/0929866521666131223143913. Protein Pept Lett. 2014. PMID: 24364859

2

The discovery of a novel and selective inhibitor of PTP1B over TCPTP: 3D QSAR pharmacophore modeling, virtual screening, synthesis, and biological evaluation.

Ma Y, Jin YY, Wang YL, Wang RL, Lu XH, Kong DX, Xu WR. Ma Y, et al. Among authors: kong dx. Chem Biol Drug Des. 2014 Jun;83(6):697-709. doi: 10.1111/cbdd.12283. Chem Biol Drug Des. 2014. PMID: 24418013

3

Discovery of Novel PI3Kδ Inhibitors Based on the p110δ Crystal Structure.

Jia W, Luo S, Zhao W, Xu W, Zhong Y, Kong D. Jia W, et al. Molecules. 2022 Sep 21;27(19):6211. doi: 10.3390/molecules27196211. Molecules. 2022. PMID: 36234743 Free PMC article.

4

JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.

Kong D, Yamori T. Kong D, et al. Bioorg Med Chem. 2012 Mar 15;20(6):1947-51. doi: 10.1016/j.bmc.2012.01.017. Epub 2012 Jan 21. Bioorg Med Chem. 2012. PMID: 22336246 Free article. Review.

5

Alkaloids from Pachysandra terminalis inhibit breast cancer invasion and have potential for development as antimetastasis therapeutic agents.

Zhai HY, Zhao C, Zhang N, Jin MN, Tang SA, Qin N, Kong DX, Duan HQ. Zhai HY, et al. Among authors: kong dx. J Nat Prod. 2012 Jul 27;75(7):1305-11. doi: 10.1021/np300207c. Epub 2012 Jul 17. J Nat Prod. 2012. PMID: 22804108

6

In vitro multifaceted activities of a specific group of novel phosphatidylinositol 3-kinase inhibitors on hotspot mutant PIK3CA.

Kong D, Yamori T, Yamazaki K, Dan S. Kong D, et al. Invest New Drugs. 2014 Dec;32(6):1134-43. doi: 10.1007/s10637-014-0152-z. Epub 2014 Aug 26. Invest New Drugs. 2014. PMID: 25152245

7

Oxyfadichalcone C inhibits melanoma A375 cell proliferation and metastasis via suppressing PI3K/Akt and MAPK/ERK pathways.

Peng X, Wang Z, Liu Y, Peng X, Liu Y, Zhu S, Zhang Z, Qiu Y, Jin M, Wang R, Zhang Q, Kong D. Peng X, et al. Life Sci. 2018 Aug 1;206:35-44. doi: 10.1016/j.lfs.2018.05.032. Epub 2018 May 18. Life Sci. 2018. PMID: 29782872

8

Selonsertib (GS-4997), an ASK1 inhibitor, antagonizes multidrug resistance in ABCB1- and ABCG2-overexpressing cancer cells.

Ji N, Yang Y, Cai CY, Lei ZN, Wang JQ, Gupta P, Shukla S, Ambudkar SV, Kong D, Chen ZS. Ji N, et al. Cancer Lett. 2019 Jan;440-441:82-93. doi: 10.1016/j.canlet.2018.10.007. Epub 2018 Oct 10. Cancer Lett. 2019. PMID: 30315846 Free PMC article.

9

In vitro antimetastatic effect of phosphatidylinositol 3-kinase inhibitor ZSTK474 on prostate cancer PC3 cells.

Zhao W, Guo W, Zhou Q, Ma SN, Wang R, Qiu Y, Jin M, Duan HQ, Kong D. Zhao W, et al. Int J Mol Sci. 2013 Jun 28;14(7):13577-91. doi: 10.3390/ijms140713577. Int J Mol Sci. 2013. PMID: 23812078 Free PMC article.

10

In vitro antitumor activity of stellettin B, a triterpene from marine sponge Jaspis stellifera, on human glioblastoma cancer SF295 cells.

Tang SA, Zhou Q, Guo WZ, Qiu Y, Wang R, Jin M, Zhang W, Li K, Yamori T, Dan S, Kong D. Tang SA, et al. Mar Drugs. 2014 Jul 15;12(7):4200-13. doi: 10.3390/md12074200. Mar Drugs. 2014. PMID: 25028795 Free PMC article.

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