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The promotion of osteoclastogenesis by sulfated hyaluronan through interference with osteoprotegerin and receptor activator of NF-κB ligand/osteoprotegerin complex formation.
Salbach-Hirsch J, Kraemer J, Rauner M, Samsonov SA, Pisabarro MT, Moeller S, Schnabelrauch M, Scharnweber D, Hofbauer LC, Hintze V. Salbach-Hirsch J, et al. Biomaterials. 2013 Oct;34(31):7653-61. doi: 10.1016/j.biomaterials.2013.06.053. Epub 2013 Jul 17. Biomaterials. 2013. PMID: 23871544
Sulfated hyaluronan improves bone regeneration of diabetic rats by binding sclerostin and enhancing osteoblast function.
Picke AK, Salbach-Hirsch J, Hintze V, Rother S, Rauner M, Kascholke C, Möller S, Bernhardt R, Rammelt S, Pisabarro MT, Ruiz-Gómez G, Schnabelrauch M, Schulz-Siegmund M, Hacker MC, Scharnweber D, Hofbauer C, Hofbauer LC. Picke AK, et al. Biomaterials. 2016 Jul;96:11-23. doi: 10.1016/j.biomaterials.2016.04.013. Epub 2016 Apr 21. Biomaterials. 2016. PMID: 27131598
Thy-1 (CD90) promotes bone formation and protects against obesity.
Picke AK, Campbell GM, Blüher M, Krügel U, Schmidt FN, Tsourdi E, Winzer M, Rauner M, Vukicevic V, Busse B, Salbach-Hirsch J, Tuckermann JP, Simon JC, Anderegg U, Hofbauer LC, Saalbach A. Picke AK, et al. Among authors: salbach hirsch j. Sci Transl Med. 2018 Aug 8;10(453):eaao6806. doi: 10.1126/scitranslmed.aao6806. Sci Transl Med. 2018. PMID: 30089635
Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling.
Rauner M, Baschant U, Roetto A, Pellegrino RM, Rother S, Salbach-Hirsch J, Weidner H, Hintze V, Campbell G, Petzold A, Lemaitre R, Henry I, Bellido T, Theurl I, Altamura S, Colucci S, Muckenthaler MU, Schett G, Komla Ebri D, Bassett JHD, Williams GR, Platzbecker U, Hofbauer LC. Rauner M, et al. Among authors: salbach hirsch j. Nat Metab. 2019 Jan;1(1):111-124. doi: 10.1038/s42255-018-0005-8. Epub 2019 Jan 7. Nat Metab. 2019. PMID: 30886999 Free PMC article.
17 results