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PIK3CA gene alterations in bladder cancer are frequent and associate with reduced recurrence in non-muscle invasive tumors.
Dueñas M, Martínez-Fernández M, García-Escudero R, Villacampa F, Marqués M, Saiz-Ladera C, Duarte J, Martínez V, Gómez MJ, Martín ML, Fernández M, Castellano D, Real FX, Rodriguez-Peralto JL, De La Rosa F, Paramio JM. Dueñas M, et al. Mol Carcinog. 2015 Jul;54(7):566-76. doi: 10.1002/mc.22125. Epub 2013 Dec 18. Mol Carcinog. 2015. PMID: 24347284
EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours.
Bornachea O, Santos M, Martínez-Cruz AB, García-Escudero R, Dueñas M, Costa C, Segrelles C, Lorz C, Buitrago A, Saiz-Ladera C, Agirre X, Grande T, Paradela B, Maraver A, Ariza JM, Prosper F, Serrano M, Sánchez-Céspedes M, Paramio JM. Bornachea O, et al. Sci Rep. 2012;2:434. doi: 10.1038/srep00434. Epub 2012 May 31. Sci Rep. 2012. PMID: 22666537 Free PMC article.
p21 suppresses inflammation and tumorigenesis on pRB-deficient stratified epithelia.
Saiz-Ladera C, Lara MF, Garín M, Ruiz S, Santos M, Lorz C, García-Escudero R, Martínez-Fernández M, Bravo A, Fernández-Capetillo O, Segrelles C, Paramio JM. Saiz-Ladera C, et al. Oncogene. 2014 Sep 11;33(37):4599-4612. doi: 10.1038/onc.2013.417. Epub 2013 Oct 14. Oncogene. 2014. PMID: 24121270 Free PMC article.
In vivo disruption of an Rb-E2F-Ezh2 signaling loop causes bladder cancer.
Santos M, Martínez-Fernández M, Dueñas M, García-Escudero R, Alfaya B, Villacampa F, Saiz-Ladera C, Costa C, Oteo M, Duarte J, Martínez V, Gómez-Rodriguez MJ, Martín ML, Fernández M, Viatour P, Morcillo MA, Sage J, Castellano D, Rodriguez-Peralto JL, de la Rosa F, Paramio JM. Santos M, et al. Cancer Res. 2014 Nov 15;74(22):6565-6577. doi: 10.1158/0008-5472.CAN-14-1218. Epub 2014 Sep 24. Cancer Res. 2014. PMID: 25252918 Free PMC article.
20 results