Kasper LH - Search Results

1

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

Kasper LH, Fukuyama T, Lerach S, Chang Y, Xu W, Wu S, Boyd KL, Brindle PK. Kasper LH, et al. PLoS One. 2013 Dec 10;8(12):e82684. doi: 10.1371/journal.pone.0082684. eCollection 2013. PLoS One. 2013. PMID: 24340053 Free PMC article.

2

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

Kasper LH, Boussouar F, Ney PA, Jackson CW, Rehg J, van Deursen JM, Brindle PK. Kasper LH, et al. Nature. 2002 Oct 17;419(6908):738-43. doi: 10.1038/nature01062. Nature. 2002. PMID: 12384703

3

Mammalian gene expression program resiliency: the roles of multiple coactivator mechanisms in hypoxia-responsive transcription.

Kasper LH, Brindle PK. Kasper LH, et al. Cell Cycle. 2006 Jan;5(2):142-6. doi: 10.4161/cc.5.2.2353. Epub 2006 Jan 16. Cell Cycle. 2006. PMID: 16357535

4

Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell development.

Kasper LH, Fukuyama T, Biesen MA, Boussouar F, Tong C, de Pauw A, Murray PJ, van Deursen JM, Brindle PK. Kasper LH, et al. Mol Cell Biol. 2006 Feb;26(3):789-809. doi: 10.1128/MCB.26.3.789-809.2006. Mol Cell Biol. 2006. PMID: 16428436 Free PMC article.

5

Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases.

Bedford DC, Kasper LH, Fukuyama T, Brindle PK. Bedford DC, et al. Among authors: kasper lh. Epigenetics. 2010 Jan 1;5(1):9-15. doi: 10.4161/epi.5.1.10449. Epub 2010 Jan 27. Epigenetics. 2010. PMID: 20110770 Free PMC article. Review.

6

CBP/p300 double null cells reveal effect of coactivator level and diversity on CREB transactivation.

Kasper LH, Lerach S, Wang J, Wu S, Jeevan T, Brindle PK. Kasper LH, et al. EMBO J. 2010 Nov 3;29(21):3660-72. doi: 10.1038/emboj.2010.235. Epub 2010 Sep 21. EMBO J. 2010. PMID: 20859256 Free PMC article.

7

Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways.

Kasper LH, Thomas MC, Zambetti GP, Brindle PK. Kasper LH, et al. Cell Cycle. 2011 Jan 15;10(2):212-21. doi: 10.4161/cc.10.2.14542. Epub 2011 Jan 15. Cell Cycle. 2011. PMID: 21220944 Free PMC article.

8

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

Bedford DC, Kasper LH, Wang R, Chang Y, Green DR, Brindle PK. Bedford DC, et al. Among authors: kasper lh. Cell Metab. 2011 Aug 3;14(2):219-30. doi: 10.1016/j.cmet.2011.06.010. Cell Metab. 2011. PMID: 21803292 Free PMC article.

9

Genome-wide and single-cell analyses reveal a context dependent relationship between CBP recruitment and gene expression.

Kasper LH, Qu C, Obenauer JC, McGoldrick DJ, Brindle PK. Kasper LH, et al. Nucleic Acids Res. 2014 Oct;42(18):11363-82. doi: 10.1093/nar/gku827. Epub 2014 Sep 23. Nucleic Acids Res. 2014. PMID: 25249627 Free PMC article.

10

Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice.

Zheng F, Kasper LH, Bedford DC, Lerach S, Teubner BJ, Brindle PK. Zheng F, et al. Among authors: kasper lh. PLoS One. 2016 Jan 5;11(1):e0146366. doi: 10.1371/journal.pone.0146366. eCollection 2016. PLoS One. 2016. PMID: 26730956 Free PMC article.

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