Do H - Search Results

1

Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours.

Wong SQ, Li J, Salemi R, Sheppard KE, Do H, Tothill RW, McArthur GA, Dobrovic A. Wong SQ, et al. Among authors: do h. Sci Rep. 2013 Dec 13;3:3494. doi: 10.1038/srep03494. Sci Rep. 2013. PMID: 24336498 Free PMC article.

2

Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies.

Do H, Dobrovic A. Do H, et al. Mol Cancer. 2009 Oct 8;8:82. doi: 10.1186/1476-4598-8-82. Mol Cancer. 2009. PMID: 19811662 Free PMC article.

3

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil- DNA glycosylase.

Do H, Dobrovic A. Do H, et al. Oncotarget. 2012 May;3(5):546-58. doi: 10.18632/oncotarget.503. Oncotarget. 2012. PMID: 22643842 Free PMC article.

4

A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma.

Richter A, Grieu F, Carrello A, Amanuel B, Namdarian K, Rynska A, Lucas A, Michael V, Bell A, Fox SB, Hewitt CA, Do H, McArthur GA, Wong SQ, Dobrovic A, Iacopetta B. Richter A, et al. Among authors: do h. Sci Rep. 2013;3:1659. doi: 10.1038/srep01659. Sci Rep. 2013. PMID: 23584600 Free PMC article.

5

Reducing sequence artifacts in amplicon-based massively parallel sequencing of formalin-fixed paraffin-embedded DNA by enzymatic depletion of uracil-containing templates.

Do H, Wong SQ, Li J, Dobrovic A. Do H, et al. Clin Chem. 2013 Sep;59(9):1376-83. doi: 10.1373/clinchem.2012.202390. Epub 2013 May 6. Clin Chem. 2013. PMID: 23649127

6

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing.

Wong SQ, Li J, Tan AY, Vedururu R, Pang JM, Do H, Ellul J, Doig K, Bell A, MacArthur GA, Fox SB, Thomas DM, Fellowes A, Parisot JP, Dobrovic A; CANCER 2015 Cohort. Wong SQ, et al. Among authors: do h. BMC Med Genomics. 2014 May 13;7:23. doi: 10.1186/1755-8794-7-23. BMC Med Genomics. 2014. PMID: 24885028 Free PMC article.

7

Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations.

Deb S, Wong SQ, Li J, Do H, Weiss J, Byrne D, Chakrabarti A, Bosma T; kConFab Investigators; Fellowes A, Dobrovic A, Fox SB. Deb S, et al. Among authors: do h. Br J Cancer. 2014 Dec 9;111(12):2351-60. doi: 10.1038/bjc.2014.511. Br J Cancer. 2014. PMID: 25490678 Free PMC article.

8

High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies.

Do H, Krypuy M, Mitchell PL, Fox SB, Dobrovic A. Do H, et al. BMC Cancer. 2008 May 21;8:142. doi: 10.1186/1471-2407-8-142. BMC Cancer. 2008. PMID: 18495026 Free PMC article.

9

Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines.

Young RJ, Waldeck K, Martin C, Foo JH, Cameron DP, Kirby L, Do H, Mitchell C, Cullinane C, Liu W, Fox SB, Dutton-Regester K, Hayward NK, Jene N, Dobrovic A, Pearson RB, Christensen JG, Randolph S, McArthur GA, Sheppard KE. Young RJ, et al. Among authors: do h. Pigment Cell Melanoma Res. 2014 Jul;27(4):590-600. doi: 10.1111/pcmr.12228. Epub 2014 Mar 6. Pigment Cell Melanoma Res. 2014. PMID: 24495407 Clinical Trial.

10

A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinoma.

Do H, Wong NC, Murone C, John T, Solomon B, Mitchell PL, Dobrovic A. Do H, et al. Sci Rep. 2014 Feb 26;4:4186. doi: 10.1038/srep04186. Sci Rep. 2014. PMID: 24569633 Free PMC article.

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