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Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity.
Steinberg GR, O'Neill HM, Dzamko NL, Galic S, Naim T, Koopman R, Jørgensen SB, Honeyman J, Hewitt K, Chen ZP, Schertzer JD, Scott JW, Koentgen F, Lynch GS, Watt MJ, van Denderen BJ, Campbell DJ, Kemp BE. Steinberg GR, et al. J Biol Chem. 2010 Nov 26;285(48):37198-209. doi: 10.1074/jbc.M110.102434. Epub 2010 Sep 20. J Biol Chem. 2010. PMID: 20855892 Free PMC article.
AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise.
O'Neill HM, Maarbjerg SJ, Crane JD, Jeppesen J, Jørgensen SB, Schertzer JD, Shyroka O, Kiens B, van Denderen BJ, Tarnopolsky MA, Kemp BE, Richter EA, Steinberg GR. O'Neill HM, et al. Among authors: steinberg gr. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16092-7. doi: 10.1073/pnas.1105062108. Epub 2011 Sep 6. Proc Natl Acad Sci U S A. 2011. PMID: 21896769 Free PMC article.
Markers of skeletal muscle mitochondrial function and lipid accumulation are moderately associated with the homeostasis model assessment index of insulin resistance in obese men.
Samjoo IA, Safdar A, Hamadeh MJ, Glover AW, Mocellin NJ, Santana J, Little JP, Steinberg GR, Raha S, Tarnopolsky MA. Samjoo IA, et al. Among authors: steinberg gr. PLoS One. 2013 Jun 12;8(6):e66322. doi: 10.1371/journal.pone.0066322. Print 2013. PLoS One. 2013. PMID: 23776659 Free PMC article.
Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance.
Henriksbo BD, Lau TC, Cavallari JF, Denou E, Chi W, Lally JS, Crane JD, Duggan BM, Foley KP, Fullerton MD, Tarnopolsky MA, Steinberg GR, Schertzer JD. Henriksbo BD, et al. Among authors: steinberg gr. Diabetes. 2014 Nov;63(11):3742-7. doi: 10.2337/db13-1398. Epub 2014 Jun 10. Diabetes. 2014. PMID: 24917577
236 results