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Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation.
Ishimoto T, Sugihara H, Watanabe M, Sawayama H, Iwatsuki M, Baba Y, Okabe H, Hidaka K, Yokoyama N, Miyake K, Yoshikawa M, Nagano O, Komohara Y, Takeya M, Saya H, Baba H. Ishimoto T, et al. Among authors: sugihara h. Carcinogenesis. 2014 May;35(5):1003-11. doi: 10.1093/carcin/bgt402. Epub 2013 Dec 6. Carcinogenesis. 2014. PMID: 24318997
Chronic inflammation with Helicobacter pylori infection is implicated in CD44 overexpression through miR-328 suppression in the gastric mucosa.
Ishimoto T, Izumi D, Watanabe M, Yoshida N, Hidaka K, Miyake K, Sugihara H, Sawayama H, Imamura Y, Iwatsuki M, Iwagami S, Baba Y, Horlad H, Komohara Y, Takeya M, Baba H. Ishimoto T, et al. Among authors: sugihara h. J Gastroenterol. 2015 Jul;50(7):751-7. doi: 10.1007/s00535-014-1019-y. Epub 2014 Dec 6. J Gastroenterol. 2015. PMID: 25479940
Small molecule agonists of PPAR-γ exert therapeutic effects in esophageal cancer.
Sawayama H, Ishimoto T, Watanabe M, Yoshida N, Sugihara H, Kurashige J, Hirashima K, Iwatsuki M, Baba Y, Oki E, Morita M, Shiose Y, Baba H. Sawayama H, et al. Among authors: sugihara h. Cancer Res. 2014 Jan 15;74(2):575-85. doi: 10.1158/0008-5472.CAN-13-1836. Epub 2013 Nov 22. Cancer Res. 2014. PMID: 24272485
CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer.
Izumi D, Ishimoto T, Miyake K, Sugihara H, Eto K, Sawayama H, Yasuda T, Kiyozumi Y, Kaida T, Kurashige J, Imamura Y, Hiyoshi Y, Iwatsuki M, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Watanabe M, Takamori H, Araki N, Tan P, Baba H. Izumi D, et al. Among authors: sugihara h. Int J Cancer. 2016 Mar 1;138(5):1207-19. doi: 10.1002/ijc.29864. Epub 2015 Oct 9. Int J Cancer. 2016. PMID: 26414794
1,031 results