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G-DOC: a systems medicine platform for personalized oncology.
Madhavan S, Gusev Y, Harris M, Tanenbaum DM, Gauba R, Bhuvaneshwar K, Shinohara A, Rosso K, Carabet LA, Song L, Riggins RB, Dakshanamurthy S, Wang Y, Byers SW, Clarke R, Weiner LM. Madhavan S, et al. Neoplasia. 2011 Sep;13(9):771-83. doi: 10.1593/neo.11806. Neoplasia. 2011. PMID: 21969811 Free PMC article.
Predicting new indications for approved drugs using a proteochemometric method.
Dakshanamurthy S, Issa NT, Assefnia S, Seshasayee A, Peters OJ, Madhavan S, Uren A, Brown ML, Byers SW. Dakshanamurthy S, et al. Among authors: madhavan s. J Med Chem. 2012 Aug 9;55(15):6832-48. doi: 10.1021/jm300576q. Epub 2012 Jul 25. J Med Chem. 2012. PMID: 22780961 Free PMC article.
Pharmacogenomic characterization of gemcitabine response--a framework for data integration to enable personalized medicine.
Harris M, Bhuvaneshwar K, Natarajan T, Sheahan L, Wang D, Tadesse MG, Shoulson I, Filice R, Steadman K, Pishvaian MJ, Madhavan S, Deeken J. Harris M, et al. Among authors: madhavan s. Pharmacogenet Genomics. 2014 Feb;24(2):81-93. doi: 10.1097/FPC.0000000000000015. Pharmacogenet Genomics. 2014. PMID: 24401833 Free PMC article. Clinical Trial.
A community effort to assess and improve drug sensitivity prediction algorithms.
Costello JC, Heiser LM, Georgii E, Gönen M, Menden MP, Wang NJ, Bansal M, Ammad-ud-din M, Hintsanen P, Khan SA, Mpindi JP, Kallioniemi O, Honkela A, Aittokallio T, Wennerberg K; NCI DREAM Community; Collins JJ, Gallahan D, Singer D, Saez-Rodriguez J, Kaski S, Gray JW, Stolovitzky G. Costello JC, et al. Nat Biotechnol. 2014 Dec;32(12):1202-12. doi: 10.1038/nbt.2877. Epub 2014 Jun 1. Nat Biotechnol. 2014. PMID: 24880487 Free PMC article.
641 results