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Page 1
Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2.
Winter E, Lecerf-Schmidt F, Gozzi G, Peres B, Lightbody M, Gauthier C, Ozvegy-Laczka C, Szakacs G, Sarkadi B, Creczynski-Pasa TB, Boumendjel A, Di Pietro A. Winter E, et al. Among authors: gauthier c. J Med Chem. 2013 Dec 27;56(24):9849-60. doi: 10.1021/jm401649j. Epub 2013 Dec 13. J Med Chem. 2013. PMID: 24304387
Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity.
Valdameri G, Gauthier C, Terreux R, Kachadourian R, Day BJ, Winnischofer SM, Rocha ME, Frachet V, Ronot X, Di Pietro A, Boumendjel A. Valdameri G, et al. Among authors: gauthier c. J Med Chem. 2012 Apr 12;55(7):3193-200. doi: 10.1021/jm2016528. Epub 2012 Apr 2. J Med Chem. 2012. PMID: 22449016 Free PMC article.
ABCG2: recent discovery of potent and highly selective inhibitors.
Lecerf-Schmidt F, Peres B, Valdameri G, Gauthier C, Winter E, Payen L, Di Pietro A, Boumendjel A. Lecerf-Schmidt F, et al. Among authors: gauthier c. Future Med Chem. 2013 Jun;5(9):1037-45. doi: 10.4155/fmc.13.71. Future Med Chem. 2013. PMID: 23734686 Review.
New structure-activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity.
Rangel LP, Winter E, Gauthier C, Terreux R, Chiaradia-Delatorre LD, Mascarello A, Nunes RJ, Yunes RA, Creczynski-Pasa TB, Macalou S, Lorendeau D, Baubichon-Cortay H, Ferreira-Pereira A, Di Pietro A. Rangel LP, et al. Among authors: gauthier c. Drug Des Devel Ther. 2013 Sep 30;7:1043-52. doi: 10.2147/DDDT.S46983. eCollection 2013. Drug Des Devel Ther. 2013. PMID: 24109177 Free PMC article.
Quinoxaline-substituted chalcones as new inhibitors of breast cancer resistance protein ABCG2: polyspecificity at B-ring position.
Winter E, Gozzi GJ, Chiaradia-Delatorre LD, Daflon-Yunes N, Terreux R, Gauthier C, Mascarello A, Leal PC, Cadena SM, Yunes RA, Nunes RJ, Creczynski-Pasa TB, Di Pietro A. Winter E, et al. Among authors: gauthier c. Drug Des Devel Ther. 2014 May 27;8:609-19. doi: 10.2147/DDDT.S56625. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 24920885 Free PMC article.
590 results