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Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β-tubulin.
Antony ML, Lee J, Hahm ER, Kim SH, Marcus AI, Kumari V, Ji X, Yang Z, Vowell CL, Wipf P, Uechi GT, Yates NA, Romero G, Sarkar SN, Singh SV. Antony ML, et al. Among authors: hahm er. J Biol Chem. 2014 Jan 17;289(3):1852-65. doi: 10.1074/jbc.M113.496844. Epub 2013 Dec 2. J Biol Chem. 2014. PMID: 24297176 Free PMC article.
Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreventive constituent of processed garlic.
Herman-Antosiewicz A, Stan SD, Hahm ER, Xiao D, Singh SV. Herman-Antosiewicz A, et al. Among authors: hahm er. Mol Cancer Ther. 2007 Apr;6(4):1249-61. doi: 10.1158/1535-7163.MCT-06-0477. Epub 2007 Apr 3. Mol Cancer Ther. 2007. PMID: 17406033
91 results