Ostermann E - Search Results

1

Pharmacodynamic and antineoplastic activity of BI 836845, a fully human IGF ligand-neutralizing antibody, and mechanistic rationale for combination with rapamycin.

Friedbichler K, Hofmann MH, Kroez M, Ostermann E, Lamche HR, Koessl C, Borges E, Pollak MN, Adolf G, Adam PJ. Friedbichler K, et al. Among authors: ostermann e. Mol Cancer Ther. 2014 Feb;13(2):399-409. doi: 10.1158/1535-7163.MCT-13-0598. Epub 2013 Dec 2. Mol Cancer Ther. 2014. PMID: 24296829

2

A novel Fc-engineered monoclonal antibody to CD37 with enhanced ADCC and high proapoptotic activity for treatment of B-cell malignancies.

Heider KH, Kiefer K, Zenz T, Volden M, Stilgenbauer S, Ostermann E, Baum A, Lamche H, Küpcü Z, Jacobi A, Müller S, Hirt U, Adolf GR, Borges E. Heider KH, et al. Among authors: ostermann e. Blood. 2011 Oct 13;118(15):4159-68. doi: 10.1182/blood-2011-04-351932. Epub 2011 Jul 27. Blood. 2011. PMID: 21795744 Free PMC article.

3

Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts.

Ostermann E, Garin-Chesa P, Heider KH, Kalat M, Lamche H, Puri C, Kerjaschki D, Rettig WJ, Adolf GR. Ostermann E, et al. Clin Cancer Res. 2008 Jul 15;14(14):4584-92. doi: 10.1158/1078-0432.CCR-07-5211. Clin Cancer Res. 2008. PMID: 18628473

4

Characterization of a high-affinity monoclonal antibody specific for CD44v6 as candidate for immunotherapy of squamous cell carcinomas.

Heider KH, Sproll M, Susani S, Patzelt E, Beaumier P, Ostermann E, Ahorn H, Adolf GR. Heider KH, et al. Among authors: ostermann e. Cancer Immunol Immunother. 1996 Dec;43(4):245-53. doi: 10.1007/s002620050329. Cancer Immunol Immunother. 1996. PMID: 9003471

5

Splice variants of the cell surface glycoprotein CD44 associated with metastatic tumour cells are expressed in normal tissues of humans and cynomolgus monkeys.

Heider KH, Mulder JW, Ostermann E, Susani S, Patzelt E, Pals ST, Adolf GR. Heider KH, et al. Among authors: ostermann e. Eur J Cancer. 1995 Dec;31A(13-14):2385-91. doi: 10.1016/0959-8049(95)00420-3. Eur J Cancer. 1995. PMID: 8652273

6

Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head-and-neck cancer xenografts.

Verel I, Heider KH, Siegmund M, Ostermann E, Patzelt E, Sproll M, Snow GB, Adolf GR, van Dongen GA. Verel I, et al. Among authors: ostermann e. Int J Cancer. 2002 May 20;99(3):396-402. doi: 10.1002/ijc.10369. Int J Cancer. 2002. PMID: 11992408

7

Human interferon omega 1: isolation of the gene, expression in Chinese hamster ovary cells and characterization of the recombinant protein.

Adolf GR, Frühbeis B, Hauptmann R, Kalsner I, Maurer-Fogy I, Ostermann E, Patzelt E, Schwendenwein R, Sommergruber W, Zöphel A. Adolf GR, et al. Among authors: ostermann e. Biochim Biophys Acta. 1991 Jun 13;1089(2):167-74. doi: 10.1016/0167-4781(91)90004-6. Biochim Biophys Acta. 1991. PMID: 1647209

8

Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment.

Kircheis R, Wightman L, Kursa M, Ostermann E, Wagner E. Kircheis R, et al. Among authors: ostermann e. Gene Ther. 2002 Jun;9(11):731-5. doi: 10.1038/sj.gt.3301748. Gene Ther. 2002. PMID: 12032698

9

Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicity.

Kircheis R, Ostermann E, Wolschek MF, Lichtenberger C, Magin-Lachmann C, Wightman L, Kursa M, Wagner E. Kircheis R, et al. Among authors: ostermann e. Cancer Gene Ther. 2002 Aug;9(8):673-80. doi: 10.1038/sj.cgt.7700487. Cancer Gene Ther. 2002. PMID: 12136428

10

Binding of cell-surface expressed CD44 to hyaluronate is dependent on splicing and cell type.

van der Voort R, Manten-Horst E, Smit L, Ostermann E, van den Berg F, Pals ST. van der Voort R, et al. Among authors: ostermann e. Biochem Biophys Res Commun. 1995 Sep 5;214(1):137-44. doi: 10.1006/bbrc.1995.2267. Biochem Biophys Res Commun. 1995. PMID: 7545390

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