Müller CR - Search Results

1

Comparative genetics of warfarin resistance.

Oldenburg J, Müller CR, Rost S, Watzka M, Bevans CG. Oldenburg J, et al. Among authors: muller cr. Hamostaseologie. 2014;34(2):143-59. doi: 10.5482/HAMO-13-09-0047. Epub 2013 Nov 29. Hamostaseologie. 2014. PMID: 24287886 Review.

2

Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces.

Czogalla KJ, Biswas A, Wendeln AC, Westhofen P, Müller CR, Watzka M, Oldenburg J. Czogalla KJ, et al. Among authors: muller cr. Blood. 2013 Oct 10;122(15):2743-50. doi: 10.1182/blood-2013-05-501692. Epub 2013 Aug 27. Blood. 2013. PMID: 23982176 Free article.

3

VKORC1: molecular target of coumarins.

Oldenburg J, Watzka M, Rost S, Müller CR. Oldenburg J, et al. Among authors: muller cr. J Thromb Haemost. 2007 Jul;5 Suppl 1:1-6. doi: 10.1111/j.1538-7836.2007.02549.x. J Thromb Haemost. 2007. PMID: 17635701 Free article. Review.

4

Thirteen novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment.

Watzka M, Geisen C, Bevans CG, Sittinger K, Spohn G, Rost S, Seifried E, Müller CR, Oldenburg J. Watzka M, et al. Among authors: muller cr. J Thromb Haemost. 2011 Jan;9(1):109-18. doi: 10.1111/j.1538-7836.2010.04095.x. J Thromb Haemost. 2011. PMID: 20946155 Free article.

5

A new cell culture-based assay quantifies vitamin K 2,3-epoxide reductase complex subunit 1 function and reveals warfarin resistance phenotypes not shown by the dithiothreitol-driven VKOR assay.

Fregin A, Czogalla KJ, Gansler J, Rost S, Taverna M, Watzka M, Bevans CG, Müller CR, Oldenburg J. Fregin A, et al. Among authors: muller cr. J Thromb Haemost. 2013 May;11(5):872-80. doi: 10.1111/jth.12185. J Thromb Haemost. 2013. PMID: 23452238 Free article.

6

VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding.

Spohn G, Kleinridders A, Wunderlich FT, Watzka M, Zaucke F, Blumbach K, Geisen C, Seifried E, Müller C, Paulsson M, Brüning JC, Oldenburg J. Spohn G, et al. Thromb Haemost. 2009 Jun;101(6):1044-50. Thromb Haemost. 2009. PMID: 19492146

7

Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin.

Rost S, Fregin A, Hünerberg M, Bevans CG, Müller CR, Oldenburg J. Rost S, et al. Among authors: muller cr. Thromb Haemost. 2005 Oct;94(4):780-6. doi: 10.1160/TH05-02-0082. Thromb Haemost. 2005. PMID: 16270630

8

Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle.

Oldenburg J, Bevans CG, Müller CR, Watzka M. Oldenburg J, et al. Among authors: muller cr. Antioxid Redox Signal. 2006 Mar-Apr;8(3-4):347-53. doi: 10.1089/ars.2006.8.347. Antioxid Redox Signal. 2006. PMID: 16677080 Review.

9

Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?

Rost S, Pelz HJ, Menzel S, MacNicoll AD, León V, Song KJ, Jäkel T, Oldenburg J, Müller CR. Rost S, et al. Among authors: muller cr. BMC Genet. 2009 Feb 6;10:4. doi: 10.1186/1471-2156-10-4. BMC Genet. 2009. PMID: 19200363 Free PMC article.

10

Human vitamin K 2,3-epoxide reductase complex subunit 1-like 1 (VKORC1L1) mediates vitamin K-dependent intracellular antioxidant function.

Westhofen P, Watzka M, Marinova M, Hass M, Kirfel G, Müller J, Bevans CG, Müller CR, Oldenburg J. Westhofen P, et al. Among authors: muller cr, muller j. J Biol Chem. 2011 Apr 29;286(17):15085-94. doi: 10.1074/jbc.M110.210971. Epub 2011 Mar 2. J Biol Chem. 2011. PMID: 21367861 Free PMC article.

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