Felsenstein KM - Search Results

1

Regenerative medicine in Alzheimer's disease.

Felsenstein KM, Candelario KM, Steindler DA, Borchelt DR. Felsenstein KM, et al. Transl Res. 2014 Apr;163(4):432-8. doi: 10.1016/j.trsl.2013.11.001. Epub 2013 Nov 8. Transl Res. 2014. PMID: 24286919 Free PMC article. Review.

2

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE, Felsenstein KM. Price AR, et al. Among authors: felsenstein km. Science. 2013 May 24;340(6135):924-d. doi: 10.1126/science.1234089. Science. 2013. PMID: 23704553

3

Reversible pathologic and cognitive phenotypes in an inducible model of Alzheimer-amyloidosis.

Melnikova T, Fromholt S, Kim H, Lee D, Xu G, Price A, Moore BD, Golde TE, Felsenstein KM, Savonenko A, Borchelt DR. Melnikova T, et al. Among authors: felsenstein km. J Neurosci. 2013 Feb 27;33(9):3765-79. doi: 10.1523/JNEUROSCI.4251-12.2013. J Neurosci. 2013. PMID: 23447589 Free PMC article.

4

Shifting a complex debate on γ-secretase cleavage and Alzheimer's disease.

Golde TE, Ran Y, Felsenstein KM. Golde TE, et al. Among authors: felsenstein km. EMBO J. 2012 May 16;31(10):2237-9. doi: 10.1038/emboj.2012.111. Epub 2012 Apr 13. EMBO J. 2012. PMID: 22505028 Free PMC article.

5

γ-Secretase inhibitors and modulators.

Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L. Golde TE, et al. Among authors: felsenstein km. Biochim Biophys Acta. 2013 Dec;1828(12):2898-907. doi: 10.1016/j.bbamem.2013.06.005. Epub 2013 Jun 17. Biochim Biophys Acta. 2013. PMID: 23791707 Free PMC article. Review.

6

Steroids as γ-secretase modulators.

Jung JI, Ladd TB, Kukar T, Price AR, Moore BD, Koo EH, Golde TE, Felsenstein KM. Jung JI, et al. Among authors: felsenstein km. FASEB J. 2013 Sep;27(9):3775-85. doi: 10.1096/fj.12-225649. Epub 2013 May 28. FASEB J. 2013. PMID: 23716494 Free PMC article.

7

The stress response neuropeptide CRF increases amyloid-β production by regulating γ-secretase activity.

Park HJ, Ran Y, Jung JI, Holmes O, Price AR, Smithson L, Ceballos-Diaz C, Han C, Wolfe MS, Daaka Y, Ryabinin AE, Kim SH, Hauger RL, Golde TE, Felsenstein KM. Park HJ, et al. Among authors: felsenstein km. EMBO J. 2015 Jun 12;34(12):1674-86. doi: 10.15252/embj.201488795. Epub 2015 May 11. EMBO J. 2015. PMID: 25964433 Free PMC article.

8

Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP).

Park HJ, Shabashvili D, Nekorchuk MD, Shyqyriu E, Jung JI, Ladd TB, Moore BD, Felsenstein KM, Golde TE, Kim SH. Park HJ, et al. Among authors: felsenstein km. J Biol Chem. 2012 Nov 23;287(48):40629-40. doi: 10.1074/jbc.M112.418442. Epub 2012 Oct 5. J Biol Chem. 2012. PMID: 23043097 Free PMC article.

9

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.

Jung JI, Price AR, Ladd TB, Ran Y, Park HJ, Ceballos-Diaz C, Smithson LA, Hochhaus G, Tang Y, Akula R, Ba S, Koo EH, Shapiro G, Felsenstein KM, Golde TE. Jung JI, et al. Among authors: felsenstein km. Mol Neurodegener. 2015 Jul 14;10:29. doi: 10.1186/s13024-015-0021-z. Mol Neurodegener. 2015. PMID: 26169917 Free PMC article.

10

γ-Secretase processing and effects of γ-secretase inhibitors and modulators on long Aβ peptides in cells.

Ran Y, Cruz PE, Ladd TB, Fauq AH, Jung JI, Matthews J, Felsenstein KM, Golde TE. Ran Y, et al. Among authors: felsenstein km. J Biol Chem. 2014 Feb 7;289(6):3276-87. doi: 10.1074/jbc.M113.512921. Epub 2013 Dec 18. J Biol Chem. 2014. PMID: 24352661 Free PMC article.

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