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Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy.
Liao C, Hsu J, Kim Y, Hu DQ, Xu D, Zhang J, Pashine A, Menke J, Whittard T, Romero N, Truitt T, Slade M, Lukacs C, Hermann J, Zhou M, Lucas M, Narula S, DeMartino J, Tan SL. Liao C, et al. Among authors: zhang j. Arthritis Res Ther. 2013 Oct 4;15(5):R146. doi: 10.1186/ar4329. Arthritis Res Ther. 2013. PMID: 24286216 Free PMC article.
RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.
Xu D, Kim Y, Postelnek J, Vu MD, Hu DQ, Liao C, Bradshaw M, Hsu J, Zhang J, Pashine A, Srinivasan D, Woods J, Levin A, O'Mahony A, Owens TD, Lou Y, Hill RJ, Narula S, DeMartino J, Fine JS. Xu D, et al. Among authors: zhang j. J Pharmacol Exp Ther. 2012 Apr;341(1):90-103. doi: 10.1124/jpet.111.187740. Epub 2012 Jan 6. J Pharmacol Exp Ther. 2012. PMID: 22228807
Thymic stromal lymphopoietin receptor blockade reduces allergic inflammation in a cynomolgus monkey model of asthma.
Cheng DT, Ma C, Niewoehner J, Dahl M, Tsai A, Zhang J, Gonsiorek W, Apparsundaram S, Pashine A, Ravindran P, Jung J, Hang J, Allard J, Bitter H, Tribouley C, Narula S, Wilson S, Fuentes ME. Cheng DT, et al. Among authors: zhang j. J Allergy Clin Immunol. 2013 Aug;132(2):455-62. doi: 10.1016/j.jaci.2013.05.011. Epub 2013 Jun 26. J Allergy Clin Immunol. 2013. PMID: 23810153
A genomic variation map provides insights into potato evolution and key agronomic traits.
Lian Q, Zhang Y, Zhang J, Peng Z, Wang W, Du M, Li H, Zhang X, Cheng L, Du R, Zhou Z, Yang Z, Xin G, Pu Y, Feng Z, Wu Q, Xuanyuan G, Bai S, Hu R, Negrão S, Bryan GJ, Bachem CWB, Zhou Y, Zhang R, Shang Y, Huang S, Lin T, Qi J. Lian Q, et al. Among authors: zhang j. Mol Plant. 2025 Jan 23:S1674-2052(25)00037-1. doi: 10.1016/j.molp.2025.01.016. Online ahead of print. Mol Plant. 2025. PMID: 39861948
180,026 results
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