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The endogenous cell-fate factor dachshund restrains prostate epithelial cell migration via repression of cytokine secretion via a cxcl signaling module.
Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, Di Sante G, Xu S, Wang Q, Li K, Sun X, Xu C, Li Z, Casimiro MC, Ertel A, Addya S, McCue PA, Lisanti MP, Wang C, Davis RJ, Mardon G, Pestell RG. Chen K, et al. Cancer Res. 2015 May 15;75(10):1992-2004. doi: 10.1158/0008-5472.CAN-14-0611. Epub 2015 Mar 13. Cancer Res. 2015. PMID: 25769723 Free PMC article.
Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells.
Casimiro MC, Di Sante G, Ju X, Li Z, Chen K, Crosariol M, Yaman I, Gormley M, Meng H, Lisanti MP, Pestell RG. Casimiro MC, et al. Among authors: chen k. Cancer Res. 2016 Jan 15;76(2):329-38. doi: 10.1158/0008-5472.CAN-15-0999. Epub 2015 Nov 18. Cancer Res. 2016. PMID: 26582866 Free PMC article.
Dachshund binds p53 to block the growth of lung adenocarcinoma cells.
Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG. Chen K, et al. Cancer Res. 2013 Jun 1;73(11):3262-74. doi: 10.1158/0008-5472.CAN-12-3191. Epub 2013 Mar 14. Cancer Res. 2013. PMID: 23492369 Free PMC article.
Cyclin D1 integrates estrogen-mediated DNA damage repair signaling.
Li Z, Chen K, Jiao X, Wang C, Willmarth NE, Casimiro MC, Li W, Ju X, Kim SH, Lisanti MP, Katzenellenbogen JA, Pestell RG. Li Z, et al. Among authors: chen k. Cancer Res. 2014 Jul 15;74(14):3959-70. doi: 10.1158/0008-5472.CAN-13-3137. Epub 2014 May 15. Cancer Res. 2014. PMID: 24830723 Free PMC article.
Loss of Sirt1 promotes prostatic intraepithelial neoplasia, reduces mitophagy, and delays PARK2 translocation to mitochondria.
Di Sante G, Pestell TG, Casimiro MC, Bisetto S, Powell MJ, Lisanti MP, Cordon-Cardo C, Castillo-Martin M, Bonal DM, Debattisti V, Chen K, Wang L, He X, McBurney MW, Pestell RG. Di Sante G, et al. Among authors: chen k. Am J Pathol. 2015 Jan;185(1):266-79. doi: 10.1016/j.ajpath.2014.09.014. Am J Pathol. 2015. PMID: 25529796 Free PMC article.
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