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The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time.
Josefsson L, von Stockenstrom S, Faria NR, Sinclair E, Bacchetti P, Killian M, Epling L, Tan A, Ho T, Lemey P, Shao W, Hunt PW, Somsouk M, Wylie W, Douek DC, Loeb L, Custer J, Hoh R, Poole L, Deeks SG, Hecht F, Palmer S. Josefsson L, et al. Among authors: palmer s. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4987-96. doi: 10.1073/pnas.1308313110. Epub 2013 Nov 25. Proc Natl Acad Sci U S A. 2013. PMID: 24277811 Free PMC article. Clinical Trial.
Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy.
Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, O'Shea A, Callender M, Spivak A, Brennan T, Kearney MF, Proschan MA, Mican JM, Rehm CA, Coffin JM, Mellors JW, Siliciano RF, Maldarelli F. Dinoso JB, et al. Among authors: palmer se. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9403-8. doi: 10.1073/pnas.0903107106. Epub 2009 May 22. Proc Natl Acad Sci U S A. 2009. PMID: 19470482 Free PMC article.
A randomized, controlled trial of raltegravir intensification in antiretroviral-treated, HIV-infected patients with a suboptimal CD4+ T cell response.
Hatano H, Hayes TL, Dahl V, Sinclair E, Lee TH, Hoh R, Lampiris H, Hunt PW, Palmer S, McCune JM, Martin JN, Busch MP, Shacklett BL, Deeks SG. Hatano H, et al. Among authors: palmer s. J Infect Dis. 2011 Apr 1;203(7):960-8. doi: 10.1093/infdis/jiq138. J Infect Dis. 2011. PMID: 21402547 Free PMC article. Clinical Trial.
Majority of CD4+ T cells from peripheral blood of HIV-1-infected individuals contain only one HIV DNA molecule.
Josefsson L, King MS, Makitalo B, Brännström J, Shao W, Maldarelli F, Kearney MF, Hu WS, Chen J, Gaines H, Mellors JW, Albert J, Coffin JM, Palmer SE. Josefsson L, et al. Among authors: palmer se. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11199-204. doi: 10.1073/pnas.1107729108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690402 Free PMC article.
2,685 results