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[Nicastrin].
Nishimura M. Nishimura M. Nihon Rinsho. 2011 Oct;69 Suppl 8:115-8. Nihon Rinsho. 2011. PMID: 22787765 Japanese. No abstract available.
Reconstitution of gamma-secretase by truncated presenilin (PS) fragments revealed that PS C-terminal transmembrane domain is critical for formation of gamma-secretase complex.
Shiraishi H, Marutani T, Wang HQ, Maeda Y, Kurono Y, Takashima A, Araki W, Nishimura M, Yanagisawa K, Komano H. Shiraishi H, et al. Among authors: nishimura m. Genes Cells. 2006 Jan;11(1):83-93. doi: 10.1111/j.1365-2443.2005.00914.x. Genes Cells. 2006. PMID: 16371134 Free article.
Alcadein cleavages by amyloid beta-precursor protein (APP) alpha- and gamma-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related gamma-secretase dysfunction.
Hata S, Fujishige S, Araki Y, Kato N, Araseki M, Nishimura M, Hartmann D, Saftig P, Fahrenholz F, Taniguchi M, Urakami K, Akatsu H, Martins RN, Yamamoto K, Maeda M, Yamamoto T, Nakaya T, Gandy S, Suzuki T. Hata S, et al. Among authors: nishimura m. J Biol Chem. 2009 Dec 25;284(52):36024-36033. doi: 10.1074/jbc.M109.057497. Epub 2009 Oct 28. J Biol Chem. 2009. PMID: 19864413 Free PMC article.
Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue.
Matsushima T, Saito Y, Elliott JI, Iijima-Ando K, Nishimura M, Kimura N, Hata S, Yamamoto T, Nakaya T, Suzuki T. Matsushima T, et al. Among authors: nishimura m. J Biol Chem. 2012 Jun 1;287(23):19715-24. doi: 10.1074/jbc.M111.334847. Epub 2012 Apr 17. J Biol Chem. 2012. PMID: 22511769 Free PMC article.
4,526 results