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A conserved role for ALG10/ALG10B and the N -glycosylation pathway in the sleep-epilepsy axis.
Gill S, Mandigo TR, Elmali AD, Leger BS, Yang B, Tran S, Laosuntisuk K, Lane JM, Bannister D, Aonbangkhen C, Ormerod KG, Mahama B, Schuch KN, Elya C, Akhund-Zade J, Math SR, LoRocco NC, Seo S, Maher M, Kanca O, Bebek N, Karadeniz D, Senel GB, Courage C, Lehesjoki AE, Winkelman JW, Bellen HJ, de Bivort B, Hart AC, Littleton JT, Baykan B, Doherty CJ, Melkani GC, Prober DA, Woo CM, Saxena R, Schreiber SL, Walker JA. Gill S, et al. Among authors: schreiber sl. medRxiv [Preprint]. 2024 Dec 13:2024.12.11.24318624. doi: 10.1101/2024.12.11.24318624. medRxiv. 2024. PMID: 39711723 Free PMC article. Preprint.
Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.
Luth MR, Godinez-Macias KP, Chen D, Okombo J, Thathy V, Cheng X, Daggupati S, Davies H, Dhingra SK, Economy JM, Edgar RCS, Gomez-Lorenzo MG, Istvan ES, Jado JC, LaMonte GM, Melillo B, Mok S, Narwal SK, Ndiaye T, Ottilie S, Palomo Diaz S, Park H, Peña S, Rocamora F, Sakata-Kato T, Small-Saunders JL, Summers RL, Tumwebaze PK, Vanaerschot M, Xia G, Yeo T, You A, Gamo FJ, Goldberg DE, Lee MCS, McNamara CW, Ndiaye D, Rosenthal PJ, Schreiber SL, Serra G, De Siqueira-Neto JL, Skinner-Adams TS, Uhlemann AC, Kato N, Lukens AK, Wirth DF, Fidock DA, Winzeler EA. Luth MR, et al. Among authors: schreiber sl. Science. 2024 Nov 29;386(6725):eadk9893. doi: 10.1126/science.adk9893. Epub 2024 Nov 29. Science. 2024. PMID: 39607932
WNT5B drives osteosarcoma stemness, chemoresistance and metastasis.
Perkins RS, Murray G, Suthon S, Davis L, Perkins NB 3rd, Fletcher L, Bozzi A, Schreiber SL, Lin J, Laxton S, Pillai RR, Wright AJ, Miranda-Carboni GA, Krum SA. Perkins RS, et al. Among authors: schreiber sl. Clin Transl Med. 2024 May;14(5):e1670. doi: 10.1002/ctm2.1670. Clin Transl Med. 2024. PMID: 38689429 Free PMC article.
Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure.
Ence CC, Uddin T, Borrel J, Mittal P, Xie H, Zoller J, Sharma A, Comer E, Schreiber SL, Melillo B, Sibley LD, Chatterjee AK. Ence CC, et al. Among authors: schreiber sl. bioRxiv [Preprint]. 2024 Feb 28:2024.02.28.582607. doi: 10.1101/2024.02.28.582607. bioRxiv. 2024. Update in: ACS Infect Dis. 2024 Jun 14;10(6):2212-2221. doi: 10.1021/acsinfecdis.4c00170 PMID: 38464220 Free PMC article. Updated. Preprint.
558 results