Hashimoto T - Search Results

1

Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.

Hudry E, Dashkoff J, Roe AD, Takeda S, Koffie RM, Hashimoto T, Scheel M, Spires-Jones T, Arbel-Ornath M, Betensky R, Davidson BL, Hyman BT. Hudry E, et al. Among authors: hashimoto t. Sci Transl Med. 2013 Nov 20;5(212):212ra161. doi: 10.1126/scitranslmed.3007000. Sci Transl Med. 2013. PMID: 24259049 Free PMC article.

2

Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.

Takeda S, Hashimoto T, Roe AD, Hori Y, Spires-Jones TL, Hyman BT. Takeda S, et al. Among authors: hashimoto t. FASEB J. 2013 Aug;27(8):3239-48. doi: 10.1096/fj.13-229666. Epub 2013 May 2. FASEB J. 2013. PMID: 23640054 Free PMC article.

3

Role of Apolipoprotein E in β-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aβ IN VITRO AND BRAIN Aβ DEPOSITION IN VIVO.

Hori Y, Hashimoto T, Nomoto H, Hyman BT, Iwatsubo T. Hori Y, et al. Among authors: hashimoto t. J Biol Chem. 2015 Jun 12;290(24):15163-74. doi: 10.1074/jbc.M114.622209. Epub 2015 Apr 27. J Biol Chem. 2015. PMID: 25918154 Free PMC article.

4

Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.

Arbel-Ornath M, Hudry E, Boivin JR, Hashimoto T, Takeda S, Kuchibhotla KV, Hou S, Lattarulo CR, Belcher AM, Shakerdge N, Trujillo PB, Muzikansky A, Betensky RA, Hyman BT, Bacskai BJ. Arbel-Ornath M, et al. Among authors: hashimoto t. Mol Neurodegener. 2017 Mar 21;12(1):27. doi: 10.1186/s13024-017-0169-9. Mol Neurodegener. 2017. PMID: 28327181 Free PMC article.

5

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain.

Jones PB, Adams KW, Rozkalne A, Spires-Jones TL, Hshieh TT, Hashimoto T, von Armin CA, Mielke M, Bacskai BJ, Hyman BT. Jones PB, et al. Among authors: hashimoto t. PLoS One. 2011 Jan 31;6(1):e14586. doi: 10.1371/journal.pone.0014586. PLoS One. 2011. PMID: 21297948 Free PMC article.

6

Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer's disease.

Hudry E, Wu HY, Arbel-Ornath M, Hashimoto T, Matsouaka R, Fan Z, Spires-Jones TL, Betensky RA, Bacskai BJ, Hyman BT. Hudry E, et al. Among authors: hashimoto t. J Neurosci. 2012 Feb 29;32(9):3176-92. doi: 10.1523/JNEUROSCI.6439-11.2012. J Neurosci. 2012. PMID: 22378890 Free PMC article.

7

Activation of glycogen synthase kinase-3 beta mediates β-amyloid induced neuritic damage in Alzheimer's disease.

DaRocha-Souto B, Coma M, Pérez-Nievas BG, Scotton TC, Siao M, Sánchez-Ferrer P, Hashimoto T, Fan Z, Hudry E, Barroeta I, Serenó L, Rodríguez M, Sánchez MB, Hyman BT, Gómez-Isla T. DaRocha-Souto B, et al. Among authors: hashimoto t. Neurobiol Dis. 2012 Jan;45(1):425-37. doi: 10.1016/j.nbd.2011.09.002. Epub 2011 Sep 13. Neurobiol Dis. 2012. PMID: 21945540 Free PMC article.

8

Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β.

Koffie RM, Hashimoto T, Tai HC, Kay KR, Serrano-Pozo A, Joyner D, Hou S, Kopeikina KJ, Frosch MP, Lee VM, Holtzman DM, Hyman BT, Spires-Jones TL. Koffie RM, et al. Among authors: hashimoto t. Brain. 2012 Jul;135(Pt 7):2155-68. doi: 10.1093/brain/aws127. Epub 2012 May 26. Brain. 2012. PMID: 22637583 Free PMC article.

9

The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system.

Tai HC, Serrano-Pozo A, Hashimoto T, Frosch MP, Spires-Jones TL, Hyman BT. Tai HC, et al. Among authors: hashimoto t. Am J Pathol. 2012 Oct;181(4):1426-35. doi: 10.1016/j.ajpath.2012.06.033. Epub 2012 Aug 4. Am J Pathol. 2012. PMID: 22867711 Free PMC article.

10

Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.

Hashimoto T, Serrano-Pozo A, Hori Y, Adams KW, Takeda S, Banerji AO, Mitani A, Joyner D, Thyssen DH, Bacskai BJ, Frosch MP, Spires-Jones TL, Finn MB, Holtzman DM, Hyman BT. Hashimoto T, et al. J Neurosci. 2012 Oct 24;32(43):15181-92. doi: 10.1523/JNEUROSCI.1542-12.2012. J Neurosci. 2012. PMID: 23100439 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

7,021 results

Search Page

Filters