Raymer RA - Search Results

1

Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A.

Du LM, Nurden P, Nurden AT, Nichols TC, Bellinger DA, Jensen ES, Haberichter SL, Merricks E, Raymer RA, Fang J, Koukouritaki SB, Jacobi PM, Hawkins TB, Cornetta K, Shi Q, Wilcox DA. Du LM, et al. Among authors: raymer ra. Nat Commun. 2013;4:2773. doi: 10.1038/ncomms3773. Nat Commun. 2013. PMID: 24253479 Free PMC article.

2

Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models.

Siner JI, Samelson-Jones BJ, Crudele JM, French RA, Lee BJ, Zhou S, Merricks E, Raymer R, Nichols TC, Camire RM, Arruda VR. Siner JI, et al. Among authors: raymer r. JCI Insight. 2016 Oct 6;1(16):e89371. doi: 10.1172/jci.insight.89371. JCI Insight. 2016. PMID: 27734034 Free PMC article.

3

Portal vein delivery of viral vectors for gene therapy for hemophilia.

Sherman A, Schlachterman A, Cooper M, Merricks EP, Raymer RA, Bellinger DA, Herzog RW, Nichols TC. Sherman A, et al. Among authors: raymer ra. Methods Mol Biol. 2014;1114:413-26. doi: 10.1007/978-1-62703-761-7_27. Methods Mol Biol. 2014. PMID: 24557919 Free PMC article.

4

Sustained correction of FVII deficiency in dogs using AAV-mediated expression of zymogen FVII.

Marcos-Contreras OA, Smith SM, Bellinger DA, Raymer RA, Merricks E, Faella A, Pavani G, Zhou S, Nichols TC, High KA, Margaritis P. Marcos-Contreras OA, et al. Among authors: raymer ra. Blood. 2016 Feb 4;127(5):565-71. doi: 10.1182/blood-2015-09-671420. Epub 2015 Dec 23. Blood. 2016. PMID: 26702064 Free PMC article.

5

Soy Phosphatidylinositol-Containing Lipid Nanoparticle Prolongs the Plasma Survival and Hemostatic Efficacy of B-domain-Deleted Recombinant Canine Factor VIII in Hemophilia A Dogs.

Shetty KA, Merricks EP, Raymer R, Rigsbee N, Nichols TC, Balu-Iyer SV. Shetty KA, et al. J Pharm Sci. 2016 Aug;105(8):2459-64. doi: 10.1016/j.xphs.2016.05.023. Epub 2016 Jun 30. J Pharm Sci. 2016. PMID: 27372547 Free PMC article.

6

Protein replacement therapy and gene transfer in canine models of hemophilia A, hemophilia B, von willebrand disease, and factor VII deficiency.

Nichols TC, Dillow AM, Franck HW, Merricks EP, Raymer RA, Bellinger DA, Arruda VR, High KA. Nichols TC, et al. Among authors: raymer ra. ILAR J. 2009;50(2):144-67. doi: 10.1093/ilar.50.2.144. ILAR J. 2009. PMID: 19293459 Free PMC article. Review.

7

Severe Hemophilia A in a Male Old English Sheep Dog with a C→T Transition that Created a Premature Stop Codon in Factor VIII.

Lozier JN, Kloos MT, Merricks EP, Lemoine N, Whitford MH, Raymer RA, Bellinger DA, Nichols TC. Lozier JN, et al. Among authors: raymer ra. Comp Med. 2016;66(5):405-411. Comp Med. 2016. PMID: 27780008 Free PMC article.

8

Prevention of spontaneous bleeding in dogs with haemophilia A and haemophilia B.

Nichols TC, Raymer RA, Franck HW, Merricks EP, Bellinger DA, DeFriess N, Margaritis P, Arruda VR, Kay MA, High KA. Nichols TC, et al. Among authors: raymer ra. Haemophilia. 2010 May;16 Suppl 3(Suppl 3):19-23. doi: 10.1111/j.1365-2516.2010.02255.x. Haemophilia. 2010. PMID: 20586797 Free PMC article. Review.

9

Liver-directed lentiviral gene therapy in a dog model of hemophilia B.

Cantore A, Ranzani M, Bartholomae CC, Volpin M, Valle PD, Sanvito F, Sergi LS, Gallina P, Benedicenti F, Bellinger D, Raymer R, Merricks E, Bellintani F, Martin S, Doglioni C, D'Angelo A, VandenDriessche T, Chuah MK, Schmidt M, Nichols T, Montini E, Naldini L. Cantore A, et al. Sci Transl Med. 2015 Mar 4;7(277):277ra28. doi: 10.1126/scitranslmed.aaa1405. Sci Transl Med. 2015. PMID: 25739762 Free PMC article.

10

Neonatal or hepatocyte growth factor-potentiated adult gene therapy with a retroviral vector results in therapeutic levels of canine factor IX for hemophilia B.

Xu L, Gao C, Sands MS, Cai SR, Nichols TC, Bellinger DA, Raymer RA, McCorquodale S, Ponder KP. Xu L, et al. Among authors: raymer ra. Blood. 2003 May 15;101(10):3924-32. doi: 10.1182/blood-2002-10-3050. Epub 2003 Jan 16. Blood. 2003. PMID: 12531787 Free article.

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