Jacobi PM - Search Results

1

Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A.

Du LM, Nurden P, Nurden AT, Nichols TC, Bellinger DA, Jensen ES, Haberichter SL, Merricks E, Raymer RA, Fang J, Koukouritaki SB, Jacobi PM, Hawkins TB, Cornetta K, Shi Q, Wilcox DA. Du LM, et al. Among authors: jacobi pm. Nat Commun. 2013;4:2773. doi: 10.1038/ncomms3773. Nat Commun. 2013. PMID: 24253479 Free PMC article.

2

Critical independent regions in the VWF propeptide and mature VWF that enable normal VWF storage.

Haberichter SL, Jacobi P, Montgomery RR. Haberichter SL, et al. Blood. 2003 Feb 15;101(4):1384-91. doi: 10.1182/blood-2002-07-2281. Epub 2002 Oct 10. Blood. 2003. PMID: 12393513 Free article.

3

Mutations in the D'D3 region of VWF traditionally associated with type 1 VWD lead to quantitative and qualitative deficiencies of VWF.

White-Adams TC, Ng CJ, Jacobi PM, Haberichter SL, Di Paola JA. White-Adams TC, et al. Among authors: jacobi pm. Thromb Res. 2016 Sep;145:112-8. doi: 10.1016/j.thromres.2016.08.009. Epub 2016 Aug 10. Thromb Res. 2016. PMID: 27533707 Free PMC article.

4

von Willebrand factor propeptide to antigen ratio identifies platelet activation and reduced von Willebrand factor survival phenotype in mice.

Jacobi PM, Kanaji S, Jakab D, Gehrand AL, Johnsen JM, Haberichter SL. Jacobi PM, et al. J Thromb Haemost. 2018 Mar;16(3):546-554. doi: 10.1111/jth.13934. Epub 2018 Jan 24. J Thromb Haemost. 2018. PMID: 29285851 Free PMC article.

5

Intersection of mechanisms of type 2A VWD through defects in VWF multimerization, secretion, ADAMTS-13 susceptibility, and regulated storage.

Jacobi PM, Gill JC, Flood VH, Jakab DA, Friedman KD, Haberichter SL. Jacobi PM, et al. Blood. 2012 May 10;119(19):4543-53. doi: 10.1182/blood-2011-06-360875. Epub 2012 Mar 19. Blood. 2012. PMID: 22431572 Free PMC article.

6

Collagen binding provides a sensitive screen for variant von Willebrand disease.

Flood VH, Gill JC, Friedman KD, Christopherson PA, Jacobi PM, Hoffmann RG, Montgomery RR, Haberichter SL; Zimmerman Program Investigators. Flood VH, et al. Among authors: jacobi pm. Clin Chem. 2013 Apr;59(4):684-91. doi: 10.1373/clinchem.2012.199000. Epub 2013 Jan 22. Clin Chem. 2013. PMID: 23340442 Free PMC article.

7

Variable content of von Willebrand factor mutant monomer drives the phenotypic variability in a family with von Willebrand disease.

Chen J, Hinckley JD, Haberichter S, Jacobi P, Montgomery R, Flood VH, Wong R, Interlandi G, Chung DW, López JA, Di Paola J. Chen J, et al. Blood. 2015 Jul 9;126(2):262-9. doi: 10.1182/blood-2014-11-613935. Epub 2015 May 27. Blood. 2015. PMID: 26019279 Free PMC article.

8

Crucial role for the VWF A1 domain in binding to type IV collagen.

Flood VH, Schlauderaff AC, Haberichter SL, Slobodianuk TL, Jacobi PM, Bellissimo DB, Christopherson PA, Friedman KD, Gill JC, Hoffmann RG, Montgomery RR; Zimmerman Program Investigators. Flood VH, et al. Among authors: jacobi pm. Blood. 2015 Apr 2;125(14):2297-304. doi: 10.1182/blood-2014-11-610824. Epub 2015 Feb 6. Blood. 2015. PMID: 25662333 Free PMC article.

9

Genome-wide studies of von Willebrand factor propeptide identify loci contributing to variation in propeptide levels and von Willebrand factor clearance.

Ozel AB, McGee B, Siemieniak D, Jacobi PM, Haberichter SL, Brody LC, Mills JL, Molloy AM, Ginsburg D, Li JZ, Desch KC. Ozel AB, et al. Among authors: jacobi pm. J Thromb Haemost. 2016 Sep;14(9):1888-98. doi: 10.1111/jth.13401. Epub 2016 Aug 19. J Thromb Haemost. 2016. PMID: 27359253 Free PMC article.

10

Homozygous type 2N R854W von Willebrand factor is poorly secreted and causes a severe von Willebrand disease phenotype.

Castaman G, Giacomelli SH, Jacobi P, Obser T, Budde U, Rodeghiero F, Haberichter SL, Schneppenheim R. Castaman G, et al. J Thromb Haemost. 2010 Sep;8(9):2011-6. doi: 10.1111/j.1538-7836.2010.03971.x. J Thromb Haemost. 2010. PMID: 20586924 Free article.

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