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Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
Navis AC, Niclou SP, Fack F, Stieber D, van Lith S, Verrijp K, Wright A, Stauber J, Tops B, Otte-Holler I, Wevers RA, van Rooij A, Pusch S, von Deimling A, Tigchelaar W, van Noorden CJ, Wesseling P, Leenders WP. Navis AC, et al. Among authors: tigchelaar w. Acta Neuropathol Commun. 2013 May 29;1:18. doi: 10.1186/2051-5960-1-18. Acta Neuropathol Commun. 2013. PMID: 24252742 Free PMC article.
Differential activity of NADPH-producing dehydrogenases renders rodents unsuitable models to study IDH1R132 mutation effects in human glioblastoma.
Atai NA, Renkema-Mills NA, Bosman J, Schmidt N, Rijkeboer D, Tigchelaar W, Bosch KS, Troost D, Jonker A, Bleeker FE, Miletic H, Bjerkvig R, De Witt Hamer PC, Van Noorden CJ. Atai NA, et al. Among authors: tigchelaar w. J Histochem Cytochem. 2011 May;59(5):489-503. doi: 10.1369/0022155411400606. Epub 2011 Feb 10. J Histochem Cytochem. 2011. PMID: 21527585 Free PMC article.
32 results