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Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.
Navis AC, Niclou SP, Fack F, Stieber D, van Lith S, Verrijp K, Wright A, Stauber J, Tops B, Otte-Holler I, Wevers RA, van Rooij A, Pusch S, von Deimling A, Tigchelaar W, van Noorden CJ, Wesseling P, Leenders WP. Navis AC, et al. Among authors: stieber d. Acta Neuropathol Commun. 2013 May 29;1:18. doi: 10.1186/2051-5960-1-18. Acta Neuropathol Commun. 2013. PMID: 24252742 Free PMC article.
Novel ways to target brain tumour metabolism.
Stieber D, Abdul Rahim SA, Niclou SP. Stieber D, et al. Expert Opin Ther Targets. 2011 Oct;15(10):1227-39. doi: 10.1517/14728222.2011.588211. Epub 2011 Jun 2. Expert Opin Ther Targets. 2011. PMID: 21635150 Review.
A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.
Klink B, Miletic H, Stieber D, Huszthy PC, Campos Valenzuela JA, Balss J, Wang J, Schubert M, Sakariassen PØ, Sundstrøm T, Torsvik A, Aarhus M, Mahesparan R, von Deimling A, Kaderali L, Niclou SP, Schröck E, Bjerkvig R, Nigro JM. Klink B, et al. Among authors: stieber d. PLoS One. 2013;8(3):e59773. doi: 10.1371/journal.pone.0059773. Epub 2013 Mar 19. PLoS One. 2013. PMID: 23527265 Free PMC article.
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.
Fack F, Espedal H, Keunen O, Golebiewska A, Obad N, Harter PN, Mittelbronn M, Bähr O, Weyerbrock A, Stuhr L, Miletic H, Sakariassen PØ, Stieber D, Rygh CB, Lund-Johansen M, Zheng L, Gottlieb E, Niclou SP, Bjerkvig R. Fack F, et al. Among authors: stieber d. Acta Neuropathol. 2015 Jan;129(1):115-31. doi: 10.1007/s00401-014-1352-5. Epub 2014 Oct 17. Acta Neuropathol. 2015. PMID: 25322816 Free PMC article.
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.
Golebiewska A, Hau AC, Oudin A, Stieber D, Yabo YA, Baus V, Barthelemy V, Klein E, Bougnaud S, Keunen O, Wantz M, Michelucci A, Neirinckx V, Muller A, Kaoma T, Nazarov PV, Azuaje F, De Falco A, Flies B, Richart L, Poovathingal S, Arns T, Grzyb K, Mock A, Herold-Mende C, Steino A, Brown D, May P, Miletic H, Malta TM, Noushmehr H, Kwon YJ, Jahn W, Klink B, Tanner G, Stead LF, Mittelbronn M, Skupin A, Hertel F, Bjerkvig R, Niclou SP. Golebiewska A, et al. Among authors: stieber d. Acta Neuropathol. 2020 Dec;140(6):919-949. doi: 10.1007/s00401-020-02226-7. Epub 2020 Oct 3. Acta Neuropathol. 2020. PMID: 33009951 Free PMC article.
Tumor versus stromal cells in culture--survival of the fittest?
Talasila KM, Brekka N, Mangseth K, Stieber D, Evensen L, Rosland GV, Torsvik A, Wagner M, Niclou SP, Mahesparan R, Vintermyr OK, Bjerkvig R, Nigro JM, Miletic H. Talasila KM, et al. Among authors: stieber d. PLoS One. 2013 Dec 2;8(12):e81183. doi: 10.1371/journal.pone.0081183. eCollection 2013. PLoS One. 2013. PMID: 24349039 Free PMC article.
EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis.
Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Stieber D, Keunen O, Brekka N, Moen I, Nigro JM, Vintermyr OK, Lund-Johansen M, Niclou S, Mørk SJ, Enger PO, Bjerkvig R, Miletic H. Talasila KM, et al. Among authors: stieber d. Acta Neuropathol. 2013 May;125(5):683-98. doi: 10.1007/s00401-013-1101-1. Epub 2013 Feb 22. Acta Neuropathol. 2013. PMID: 23429996 Free PMC article.
34 results