Gaj T - Search Results

1

Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors.

Mercer AC, Gaj T, Sirk SJ, Lamb BM, Barbas CF 3rd. Mercer AC, et al. Among authors: gaj t. ACS Synth Biol. 2014 Oct 17;3(10):723-30. doi: 10.1021/sb400114p. Epub 2013 Nov 22. ACS Synth Biol. 2014. PMID: 24251925 Free PMC article.

2

Chimeric TALE recombinases with programmable DNA sequence specificity.

Mercer AC, Gaj T, Fuller RP, Barbas CF 3rd. Mercer AC, et al. Among authors: gaj t. Nucleic Acids Res. 2012 Nov;40(21):11163-72. doi: 10.1093/nar/gks875. Epub 2012 Sep 26. Nucleic Acids Res. 2012. PMID: 23019222 Free PMC article.

3

A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells.

Gaj T, Mercer AC, Sirk SJ, Smith HL, Barbas CF 3rd. Gaj T, et al. Nucleic Acids Res. 2013 Apr 1;41(6):3937-46. doi: 10.1093/nar/gkt071. Epub 2013 Feb 7. Nucleic Acids Res. 2013. PMID: 23393187 Free PMC article.

4

Cell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineering.

Liu J, Gaj T, Patterson JT, Sirk SJ, Barbas CF 3rd. Liu J, et al. Among authors: gaj t. PLoS One. 2014 Jan 20;9(1):e85755. doi: 10.1371/journal.pone.0085755. eCollection 2014. PLoS One. 2014. PMID: 24465685 Free PMC article.

5

Enhancing the specificity of recombinase-mediated genome engineering through dimer interface redesign.

Gaj T, Sirk SJ, Tingle RD, Mercer AC, Wallen MC, Barbas CF 3rd. Gaj T, et al. J Am Chem Soc. 2014 Apr 2;136(13):5047-56. doi: 10.1021/ja4130059. Epub 2014 Mar 20. J Am Chem Soc. 2014. PMID: 24611715 Free PMC article.

6

Genome engineering with custom recombinases.

Gaj T, Barbas CF 3rd. Gaj T, et al. Methods Enzymol. 2014;546:79-91. doi: 10.1016/B978-0-12-801185-0.00004-0. Methods Enzymol. 2014. PMID: 25398336

7

Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors.

Perdigão P, Gaj T, Santa-Marta M, Barbas CF 3rd, Goncalves J. Perdigão P, et al. Among authors: gaj t. PLoS One. 2016 Mar 2;11(3):e0150037. doi: 10.1371/journal.pone.0150037. eCollection 2016. PLoS One. 2016. PMID: 26933881 Free PMC article.

8

Directed evolution of recombinase specificity by split gene reassembly.

Gersbach CA, Gaj T, Gordley RM, Barbas CF 3rd. Gersbach CA, et al. Among authors: gaj t. Nucleic Acids Res. 2010 Jul;38(12):4198-206. doi: 10.1093/nar/gkq125. Epub 2010 Mar 1. Nucleic Acids Res. 2010. PMID: 20194120 Free PMC article.

9

Directed evolution of an enhanced and highly efficient FokI cleavage domain for zinc finger nucleases.

Guo J, Gaj T, Barbas CF 3rd. Guo J, et al. Among authors: gaj t. J Mol Biol. 2010 Jul 2;400(1):96-107. doi: 10.1016/j.jmb.2010.04.060. Epub 2010 May 4. J Mol Biol. 2010. PMID: 20447404 Free PMC article.

10

Structure-guided reprogramming of serine recombinase DNA sequence specificity.

Gaj T, Mercer AC, Gersbach CA, Gordley RM, Barbas CF 3rd. Gaj T, et al. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):498-503. doi: 10.1073/pnas.1014214108. Epub 2010 Dec 27. Proc Natl Acad Sci U S A. 2011. PMID: 21187418 Free PMC article.

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