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Modification of picornavirus genomic RNA using 'click' chemistry shows that unlinking of the VPg peptide is dispensable for translation and replication of the incoming viral RNA.
Langereis MA, Feng Q, Nelissen FH, Virgen-Slane R, van der Heden van Noort GJ, Maciejewski S, Filippov DV, Semler BL, van Delft FL, van Kuppeveld FJ. Langereis MA, et al. Among authors: van der heden van noort gj, van delft fl, van kuppeveld fj. Nucleic Acids Res. 2014 Feb;42(4):2473-82. doi: 10.1093/nar/gkt1162. Epub 2013 Nov 15. Nucleic Acids Res. 2014. PMID: 24243841 Free PMC article.
2-Azidoalkoxy-7-hydro-8-oxoadenine derivatives as TLR7 agonists inducing dendritic cell maturation.
Weterings JJ, Khan S, van der Heden van Noort GJ, Melief CJ, Overkleeft HS, van der Burg SH, Ossendorp F, van der Marel GA, Filippov DV. Weterings JJ, et al. Among authors: van der heden van noort gj, van der marel ga, van der burg sh. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2249-51. doi: 10.1016/j.bmcl.2009.02.095. Epub 2009 Feb 27. Bioorg Med Chem Lett. 2009. PMID: 19299126
Synthesis of nucleotidylated poliovirus VPg proteins.
van der Heden van Noort GJ, Overkleeft HS, van der Marel GA, Filippov DV. van der Heden van Noort GJ, et al. Among authors: van der marel ga. J Org Chem. 2010 Aug 20;75(16):5733-6. doi: 10.1021/jo100757t. J Org Chem. 2010. PMID: 20704445
Fully automated sequential solid phase approach towards viral RNA-nucleopeptides.
van der Heden van Noort GJ, van Delft P, Meeuwenoord NJ, Overkleeft HS, van der Marel GA, Filippov DV. van der Heden van Noort GJ, et al. Among authors: van der marel ga, van delft p. Chem Commun (Camb). 2012 Aug 21;48(65):8093-5. doi: 10.1039/c2cc33477a. Epub 2012 Jul 10. Chem Commun (Camb). 2012. PMID: 22781550
An RNA virus hijacks an incognito function of a DNA repair enzyme.
Virgen-Slane R, Rozovics JM, Fitzgerald KD, Ngo T, Chou W, van der Heden van Noort GJ, Filippov DV, Gershon PD, Semler BL. Virgen-Slane R, et al. Among authors: van der heden van noort gj. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14634-9. doi: 10.1073/pnas.1208096109. Epub 2012 Aug 20. Proc Natl Acad Sci U S A. 2012. PMID: 22908287 Free PMC article.
54 results