Engert A - Search Results

1

The bispecific immunoligand ULBP2-aCEA redirects natural killer cells to tumor cells and reveals potent anti-tumor activity against colon carcinoma.

Rothe A, Jachimowicz RD, Borchmann S, Madlener M, Keßler J, Reiners KS, Sauer M, Hansen HP, Ullrich RT, Chatterjee S, Borchmann P, Yazaki P, Koslowsky TC, Engert A, Heukamp LC, Hallek M, von Strandmann EP. Rothe A, et al. Among authors: engert a. Int J Cancer. 2014 Jun 15;134(12):2829-40. doi: 10.1002/ijc.28609. Epub 2013 Nov 29. Int J Cancer. 2014. PMID: 24242212

2

Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin.

Hansen HP, Matthey B, Barth S, Kisseleva T, Mokros T, Davies SJ, Beckett RP, Foelster-Holst R, Lange HH, Engert A, Lemke H. Hansen HP, et al. Among authors: engert a. Int J Cancer. 2002 Mar 10;98(2):210-5. doi: 10.1002/ijc.10182. Int J Cancer. 2002. PMID: 11857410

3

A Phase I study with an anti-CD30 ricin A-chain immunotoxin (Ki-4.dgA) in patients with refractory CD30+ Hodgkin's and non-Hodgkin's lymphoma.

Schnell R, Staak O, Borchmann P, Schwartz C, Matthey B, Hansen H, Schindler J, Ghetie V, Vitetta ES, Diehl V, Engert A. Schnell R, et al. Among authors: engert a. Clin Cancer Res. 2002 Jun;8(6):1779-86. Clin Cancer Res. 2002. PMID: 12060617 Clinical Trial.

4

Phase 1 trial of the novel bispecific molecule H22xKi-4 in patients with refractory Hodgkin lymphoma.

Borchmann P, Schnell R, Fuss I, Manzke O, Davis T, Lewis LD, Behnke D, Wickenhauser C, Schiller P, Diehl V, Engert A. Borchmann P, et al. Among authors: engert a. Blood. 2002 Nov 1;100(9):3101-7. doi: 10.1182/blood-2001-12-0295. Blood. 2002. PMID: 12384405 Free article. Clinical Trial.

5

A novel approach for immunization, screening and characterization of selected scFv libraries using membrane fractions of tumor cells.

Tur MK, Rothe A, Huhn M, Goerres U, Klimka A, Stöcker M, Engert A, Fischer R, Finner R, Barth S. Tur MK, et al. Among authors: engert a. Int J Mol Med. 2003 Apr;11(4):523-7. Int J Mol Med. 2003. PMID: 12632108

6

The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma.

Borchmann P, Treml JF, Hansen H, Gottstein C, Schnell R, Staak O, Zhang HF, Davis T, Keler T, Diehl V, Graziano RF, Engert A. Borchmann P, et al. Among authors: engert a. Blood. 2003 Nov 15;102(10):3737-42. doi: 10.1182/blood-2003-02-0515. Epub 2003 Jul 24. Blood. 2003. PMID: 12881320 Free article.

7

The ectodomain shedding of CD30 is specifically regulated by peptide motifs in its cysteine-rich domains 2 and 5.

Hansen HP, Recke A, Reineke U, Von Tresckow B, Borchmann P, Von Strandmann EP, Lange H, Lemke H, Engert A. Hansen HP, et al. Among authors: engert a. FASEB J. 2004 May;18(7):893-5. doi: 10.1096/fj.03-0901fje. Epub 2004 Mar 19. FASEB J. 2004. PMID: 15033921

8

Depletion of cellular cholesterol and lipid rafts increases shedding of CD30.

von Tresckow B, Kallen KJ, von Strandmann EP, Borchmann P, Lange H, Engert A, Hansen HP. von Tresckow B, et al. Among authors: engert a. J Immunol. 2004 Apr 1;172(7):4324-31. doi: 10.4049/jimmunol.172.7.4324. J Immunol. 2004. PMID: 15034047

9

Selective killing of B-cell hybridomas targeting proteinase 3, Wegener's autoantigen.

Reiners KS, Hansen HP, Krüssmann A, Schön G, Csernok E, Gross WL, Engert A, Von Strandmann EP. Reiners KS, et al. Among authors: engert a. Immunology. 2004 Jun;112(2):228-36. doi: 10.1111/j.1365-2567.2004.01875.x. Immunology. 2004. PMID: 15147566 Free PMC article.

10

Metalloproteinase inhibition augments antitumor efficacy of the anti-CD30 immunotoxin Ki-3(scFv)-ETA' against human lymphomas in vivo.

Matthey B, Borchmann P, Schnell R, Tawadros S, Lange H, Huhn M, Klimka A, Tur MK, Barth S, Engert A, Hansen HP. Matthey B, et al. Among authors: engert a. Int J Cancer. 2004 Sep 10;111(4):568-74. doi: 10.1002/ijc.20278. Int J Cancer. 2004. PMID: 15239135

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