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Intermittent hypoxia-induced increases in reactive oxygen species activate NFATc3 increasing endothelin-1 vasoconstrictor reactivity.
Friedman JK, Nitta CH, Henderson KM, Codianni SJ, Sanchez L, Ramiro-Diaz JM, Howard TA, Giermakowska W, Kanagy NL, Gonzalez Bosc LV. Friedman JK, et al. Among authors: nitta ch. Vascul Pharmacol. 2014 Jan;60(1):17-24. doi: 10.1016/j.vph.2013.11.001. Epub 2013 Nov 15. Vascul Pharmacol. 2014. PMID: 24239798 Free PMC article.
NFATc3 contributes to intermittent hypoxia-induced arterial remodeling in mice.
de Frutos S, Caldwell E, Nitta CH, Kanagy NL, Wang J, Wang W, Walker MK, Gonzalez Bosc LV. de Frutos S, et al. Among authors: nitta ch. Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H356-63. doi: 10.1152/ajpheart.00341.2010. Epub 2010 May 21. Am J Physiol Heart Circ Physiol. 2010. PMID: 20495147 Free PMC article.