Inazuka M - Search Results

1

Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins.

Tanaka Y, Aikawa K, Nishida G, Homma M, Sogabe S, Igaki S, Hayano Y, Sameshima T, Miyahisa I, Kawamoto T, Tawada M, Imai Y, Inazuka M, Cho N, Imaeda Y, Ishikawa T. Tanaka Y, et al. Among authors: inazuka m. J Med Chem. 2013 Dec 12;56(23):9635-45. doi: 10.1021/jm401170c. Epub 2013 Dec 2. J Med Chem. 2013. PMID: 24215352

2

Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.

Tanaka Y, Seto M, Kakegawa K, Takami K, Kikuchi F, Yamamoto T, Nakamura M, Daini M, Murakami M, Ohashi T, Kasahara T, Wang J, Ikeda Z, Wada Y, Puenner F, Fujii T, Inazuka M, Sato S, Suzaki T, Oak JH, Takai Y, Kohara H, Kimoto K, Oki H, Mikami S, Sasaki M, Tanaka Y. Tanaka Y, et al. Among authors: inazuka m. J Med Chem. 2022 Mar 10;65(5):4270-4290. doi: 10.1021/acs.jmedchem.1c02078. Epub 2022 Feb 21. J Med Chem. 2022. PMID: 35188773 Free article.

3

T-3256336, a novel and orally available small molecule IAP antagonist, induced tumor cell death via induction of systemic TNF alpha production.

Sumi H, Inazuka M, Hashimoto K, Ishikawa T, Yoshida S, Yabuki M. Sumi H, et al. Among authors: inazuka m. Biochem Biophys Res Commun. 2016 Oct 14;479(2):179-185. doi: 10.1016/j.bbrc.2016.09.019. Epub 2016 Sep 5. Biochem Biophys Res Commun. 2016. PMID: 27608596

4

An inhibitor of apoptosis protein antagonist T-3256336 potentiates the antitumor efficacy of the Nedd8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924).

Sumi H, Inazuka M, Morimoto M, Hibino R, Hashimoto K, Ishikawa T, Kuida K, Smith PG, Yoshida S, Yabuki M. Sumi H, et al. Among authors: inazuka m. Biochem Biophys Res Commun. 2016 Nov 18;480(3):380-386. doi: 10.1016/j.bbrc.2016.10.058. Epub 2016 Oct 19. Biochem Biophys Res Commun. 2016. PMID: 27771247

5

Antitumor activity and pharmacodynamic biomarkers of a novel and orally available small-molecule antagonist of inhibitor of apoptosis proteins.

Sumi H, Yabuki M, Iwai K, Morimoto M, Hibino R, Inazuka M, Hashimoto K, Kosugi Y, Aoyama K, Yamamoto S, Yoshimatsu M, Yamasaki H, Tozawa R, Ishikawa T, Yoshida S. Sumi H, et al. Among authors: inazuka m. Mol Cancer Ther. 2013 Feb;12(2):230-40. doi: 10.1158/1535-7163.MCT-12-0699. Epub 2012 Dec 12. Mol Cancer Ther. 2013. PMID: 23243058

6

Acute subdural hematoma associated with disruption of tumor vessels due to rapid growth of falx meningioma: A case report and literature review.

Oyamada K, Ohbuchi H, Nishiyama K, Imazato D, Inazuka M, Hagiwara S, Kubota Y. Oyamada K, et al. Among authors: inazuka m. Surg Neurol Int. 2022 Oct 28;13:495. doi: 10.25259/SNI_553_2022. eCollection 2022. Surg Neurol Int. 2022. PMID: 36447859 Free PMC article.

7

Optimal timing and safety of the external ventricular drainage in patients with high-grade aneurysmal subarachnoid hemorrhage treated with endovascular coiling.

Ohbuchi H, Hagiwara S, Arai N, Yoneyama T, Takahashi Y, Inazuka M, Kubota Y, Chernov M, Kasuya H. Ohbuchi H, et al. Among authors: inazuka m. J Clin Neurosci. 2021 Jun;88:63-69. doi: 10.1016/j.jocn.2021.03.003. Epub 2021 Mar 31. J Clin Neurosci. 2021. PMID: 33992206

8

Characteristics and management of the offending veins in microvascular decompression surgery for trigeminal neuralgia.

Kasuya H, Tani S, Kubota Y, Yokosako S, Ohbuchi H, Arai N, Inazuka M, Chernov M. Kasuya H, et al. Among authors: inazuka m. Neurosurg Rev. 2021 Aug;44(4):2337-2347. doi: 10.1007/s10143-020-01411-2. Epub 2020 Oct 27. Neurosurg Rev. 2021. PMID: 33111206 Free PMC article.

9

Aggressive internal and external decompression as a life-saving surgery in a deeply comatose patient with fixed dilated pupils after severe traumatic brain injury: A case report.

Ebise H, Kubota Y, Ohbuchi H, Arai N, Inazuka M, Chernov M, Kasuya H. Ebise H, et al. Among authors: inazuka m. Surg Neurol Int. 2020 Jul 11;11:181. doi: 10.25259/SNI_271_2020. eCollection 2020. Surg Neurol Int. 2020. PMID: 32754356 Free PMC article.

10

Continuous intrathecal injection therapy of methotrexate is a therapeutic option in primary CNS lymphoma.

Otani R, Yamada R, Kushihara Y, Inazuka M, Shinoura N. Otani R, et al. Among authors: inazuka m. J Clin Neurosci. 2019 Nov;69:26-30. doi: 10.1016/j.jocn.2019.08.083. Epub 2019 Aug 26. J Clin Neurosci. 2019. PMID: 31466902

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