Voorman R - Search Results

1

The role of lymphatic transport on the systemic bioavailability of the Bcl-2 protein family inhibitors navitoclax (ABT-263) and ABT-199.

Choo EF, Boggs J, Zhu C, Lubach JW, Catron ND, Jenkins G, Souers AJ, Voorman R. Choo EF, et al. Among authors: voorman r. Drug Metab Dispos. 2014 Feb;42(2):207-12. doi: 10.1124/dmd.113.055053. Epub 2013 Nov 8. Drug Metab Dispos. 2014. PMID: 24212376

2

Disposition and drug-drug interaction potential of veliparib (ABT-888), a novel and potent inhibitor of poly(ADP-ribose) polymerase.

Li X, Delzer J, Voorman R, de Morais SM, Lao Y. Li X, et al. Among authors: voorman r. Drug Metab Dispos. 2011 Jul;39(7):1161-9. doi: 10.1124/dmd.110.037820. Epub 2011 Mar 24. Drug Metab Dispos. 2011. PMID: 21436403

3

Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).

Kikuchi R, Lao Y, Bow DA, Chiou WJ, Andracki ME, Carr RA, Voorman RL, De Morais SM. Kikuchi R, et al. Among authors: voorman rl. J Pharm Sci. 2013 Dec;102(12):4426-32. doi: 10.1002/jps.23737. Epub 2013 Oct 2. J Pharm Sci. 2013. PMID: 24122511

4

Absorption, distribution, metabolism, and excretion of atevirdine in the rat.

Chang M, Sood VK, Wilson GJ, Kloosterman DA, Sanders PE, Schuette MR, Judy RW, Voorman RL, Maio SM, Slatter JG. Chang M, et al. Among authors: voorman rl. Drug Metab Dispos. 1998 Oct;26(10):1008-18. Drug Metab Dispos. 1998. PMID: 9763407

5

Metabolism of delavirdine, a human immunodeficiency virus type-1 reverse transcriptase inhibitor, by microsomal cytochrome P450 in humans, rats, and other species: probable involvement of CYP2D6 and CYP3A.

Voorman RL, Maio SM, Hauer MJ, Sanders PE, Payne NA, Ackland MJ. Voorman RL, et al. Drug Metab Dispos. 1998 Jul;26(7):631-9. Drug Metab Dispos. 1998. PMID: 9660845

6

Metabolic aromatization of N-alkyl-1,2,3,4-tetrahydroquinoline substructures to quinolinium by human liver microsomes and horseradish peroxidase.

Gu C, Collins R, Holsworth DD, Walker GS, Voorman RL. Gu C, et al. Among authors: voorman rl. Drug Metab Dispos. 2006 Dec;34(12):2044-55. doi: 10.1124/dmd.106.012286. Epub 2006 Sep 19. Drug Metab Dispos. 2006. PMID: 16985099

7

In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia.

Chiou WJ, de Morais SM, Kikuchi R, Voorman RL, Li X, Bow DA. Chiou WJ, et al. Among authors: voorman rl. Xenobiotica. 2014 Mar;44(3):276-82. doi: 10.3109/00498254.2013.820006. Epub 2013 Jul 25. Xenobiotica. 2014. PMID: 23886114

8

Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.

Voorman RL, Payne NA, Wienkers LC, Hauer MJ, Sanders PE. Voorman RL, et al. Drug Metab Dispos. 2001 Jan;29(1):41-7. Drug Metab Dispos. 2001. PMID: 11124228

9

Comparison of paraben stability in human and rat skin.

Harville HM, Voorman R, Prusakiewicz JJ. Harville HM, et al. Among authors: voorman r. Drug Metab Lett. 2007 Jan;1(1):17-21. doi: 10.2174/187231207779814300. Drug Metab Lett. 2007. PMID: 19356013

10

The time to move cytochrome p450 induction into mainstream pharmacology is long overdue.

Smith DA, Dickins M, Fahmi OA, Iwasaki K, Lee C, Obach RS, Padbury G, De Morais SM, Ripp SL, Stevens J, Voorman R, Youdim K. Smith DA, et al. Among authors: voorman r. Drug Metab Dispos. 2007 Apr;35(4):697-8. doi: 10.1124/dmd.106.013284. Drug Metab Dispos. 2007. PMID: 17384203 No abstract available.

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