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436 results

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Page 1
Aurora isoform selectivity: design and synthesis of imidazo[4,5-b]pyridine derivatives as highly selective inhibitors of Aurora-A kinase in cells.
Bavetsias V, Faisal A, Crumpler S, Brown N, Kosmopoulou M, Joshi A, Atrash B, Pérez-Fuertes Y, Schmitt JA, Boxall KJ, Burke R, Sun C, Avery S, Bush K, Henley A, Raynaud FI, Workman P, Bayliss R, Linardopoulos S, Blagg J. Bavetsias V, et al. Among authors: avery s. J Med Chem. 2013 Nov 27;56(22):9122-35. doi: 10.1021/jm401115g. Epub 2013 Nov 6. J Med Chem. 2013. PMID: 24195668 Free PMC article.
Optimization of imidazo[4,5-b]pyridine-based kinase inhibitors: identification of a dual FLT3/Aurora kinase inhibitor as an orally bioavailable preclinical development candidate for the treatment of acute myeloid leukemia.
Bavetsias V, Crumpler S, Sun C, Avery S, Atrash B, Faisal A, Moore AS, Kosmopoulou M, Brown N, Sheldrake PW, Bush K, Henley A, Box G, Valenti M, de Haven Brandon A, Raynaud FI, Workman P, Eccles SA, Bayliss R, Linardopoulos S, Blagg J. Bavetsias V, et al. Among authors: avery s. J Med Chem. 2012 Oct 25;55(20):8721-34. doi: 10.1021/jm300952s. Epub 2012 Oct 8. J Med Chem. 2012. PMID: 23043539 Free PMC article.
7-(Pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine-based derivatives for kinase inhibition: Co-crystallisation studies with Aurora-A reveal distinct differences in the orientation of the pyrazole N1-substituent.
Bavetsias V, Pérez-Fuertes Y, McIntyre PJ, Atrash B, Kosmopoulou M, O'Fee L, Burke R, Sun C, Faisal A, Bush K, Avery S, Henley A, Raynaud FI, Linardopoulos S, Bayliss R, Blagg J. Bavetsias V, et al. Among authors: avery s. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4203-9. doi: 10.1016/j.bmcl.2015.08.003. Epub 2015 Aug 6. Bioorg Med Chem Lett. 2015. PMID: 26296477 Free PMC article.
Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns.
Moore AS, Faisal A, Gonzalez de Castro D, Bavetsias V, Sun C, Atrash B, Valenti M, de Haven Brandon A, Avery S, Mair D, Mirabella F, Swansbury J, Pearson AD, Workman P, Blagg J, Raynaud FI, Eccles SA, Linardopoulos S. Moore AS, et al. Among authors: avery s. Leukemia. 2012 Jul;26(7):1462-70. doi: 10.1038/leu.2012.52. Epub 2012 Feb 22. Leukemia. 2012. PMID: 22354205 Free PMC article.
Cancer research in South Asian Association for Regional Cooperation (SAARC) countries.
Huq MS, Acharya SC, Gautam M, Silwal SR, Sapkota S, Poudyal S, Sharma S, Babu KG, Nigar T, Pervin S, Gulia S, Gunasekara S, Uddin AFMK, Tshomo U, Safi AJ, Nadeem MS, Masood AI, Sumon MA, Purvin S, Hai MA, Skinner HD, Avery S, Ngwa W, Wijesooriya K. Huq MS, et al. Among authors: avery s. Lancet Oncol. 2024 Dec;25(12):e675-e684. doi: 10.1016/S1470-2045(24)00518-7. Lancet Oncol. 2024. PMID: 39637904 Review.
Cancer education and training within the South Asian Association for Regional Cooperation (SAARC) countries.
Huq MS, Acharya SC, Sapkota S, Silwal SR, Gautam M, Sharma S, Poudyal S, Sumon MA, Hossain T, Uddin AFMK, Gunasekara S, Babu KG, Malhotra H, Tshomo U, Safi AJ, Masood AI, Purvin S, Hai MA, Islam SM, Islam T, Skinner HD, Avery S, Ngwa W, Wijesooriya K. Huq MS, et al. Among authors: avery s. Lancet Oncol. 2024 Dec;25(12):e663-e674. doi: 10.1016/S1470-2045(24)00517-5. Lancet Oncol. 2024. PMID: 39637903 Review.
Cancer care and outreach in the South Asian Association for Regional Cooperation (SAARC) region: overcoming barriers and addressing challenges.
Huq MS, Acharya SC, Poudyal S, Sharma S, Silwal SR, Sapkota S, Gautam M, Haque MM, Uddin AFMK, Gunasekara S, Babu KG, Tshomo U, Safi AJ, Masood AI, Sumon MA, Purvin S, Hai MA, Skinner HD, Avery S, Ngwa W, Wijesooriya K. Huq MS, et al. Among authors: avery s. Lancet Oncol. 2024 Dec;25(12):e650-e662. doi: 10.1016/S1470-2045(24)00514-X. Lancet Oncol. 2024. PMID: 39637902
Cancer care and outreach in South Asian Association for Regional Cooperation (SAARC) countries: from epidemiology and the National Cancer Control Programme to screening, diagnosis, and treatment.
Huq MS, Acharya SC, Sharma S, Poudyal S, Sapkota S, Shrestha S, Gautam M, Silwal SR, Haque MM, Uddin AFMK, Gunasekara S, Babu KG, Tshomo U, Safi AJ, Masood AI, Sumon MA, Hai MA, Hossain A, Purvin S, Skinner HD, Avery S, Ngwa W, Wijesooriya K. Huq MS, et al. Among authors: avery s. Lancet Oncol. 2024 Dec;25(12):e639-e649. doi: 10.1016/S1470-2045(24)00521-7. Lancet Oncol. 2024. PMID: 39637901 Review.
436 results