Forman-Kay JD - Search Results

1

Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions.

Bozoky Z, Krzeminski M, Muhandiram R, Birtley JR, Al-Zahrani A, Thomas PJ, Frizzell RA, Ford RC, Forman-Kay JD. Bozoky Z, et al. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4427-36. doi: 10.1073/pnas.1315104110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191035 Free PMC article.

2

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation.

Farrow NA, Muhandiram R, Singer AU, Pascal SM, Kay CM, Gish G, Shoelson SE, Pawson T, Forman-Kay JD, Kay LE. Farrow NA, et al. Biochemistry. 1994 May 17;33(19):5984-6003. doi: 10.1021/bi00185a040. Biochemistry. 1994. PMID: 7514039

3

High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif.

Li SC, Songyang Z, Vincent SJ, Zwahlen C, Wiley S, Cantley L, Kay LE, Forman-Kay J, Pawson T. Li SC, et al. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7204-9. doi: 10.1073/pnas.94.14.7204. Proc Natl Acad Sci U S A. 1997. PMID: 9207069 Free PMC article.

4

Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity.

Finerty PJ Jr, Muhandiram R, Forman-Kay JD. Finerty PJ Jr, et al. J Mol Biol. 2002 Sep 20;322(3):605-20. doi: 10.1016/s0022-2836(02)00803-3. J Mol Biol. 2002. PMID: 12225753

5

Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide.

Donaldson LW, Gish G, Pawson T, Kay LE, Forman-Kay JD. Donaldson LW, et al. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14053-8. doi: 10.1073/pnas.212518799. Epub 2002 Oct 16. Proc Natl Acad Sci U S A. 2002. PMID: 12384576 Free PMC article.

6

Site-specific contributions to the pH dependence of protein stability.

Tollinger M, Crowhurst KA, Kay LE, Forman-Kay JD. Tollinger M, et al. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4545-50. doi: 10.1073/pnas.0736600100. Epub 2003 Apr 1. Proc Natl Acad Sci U S A. 2003. PMID: 12671071 Free PMC article.

7

NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain.

Finerty PJ Jr, Mittermaier AK, Muhandiram R, Kay LE, Forman-Kay JD. Finerty PJ Jr, et al. Biochemistry. 2005 Jan 18;44(2):694-703. doi: 10.1021/bi048641k. Biochemistry. 2005. PMID: 15641795

8

Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity.

Borg M, Mittag T, Pawson T, Tyers M, Forman-Kay JD, Chan HS. Borg M, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9650-5. doi: 10.1073/pnas.0702580104. Epub 2007 May 23. Proc Natl Acad Sci U S A. 2007. PMID: 17522259 Free PMC article.

9

CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices.

Baker JM, Hudson RP, Kanelis V, Choy WY, Thibodeau PH, Thomas PJ, Forman-Kay JD. Baker JM, et al. Nat Struct Mol Biol. 2007 Aug;14(8):738-45. doi: 10.1038/nsmb1278. Epub 2007 Jul 29. Nat Struct Mol Biol. 2007. PMID: 17660831 Free PMC article.

10

Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3.

Dorwart MR, Shcheynikov N, Baker JM, Forman-Kay JD, Muallem S, Thomas PJ. Dorwart MR, et al. J Biol Chem. 2008 Mar 28;283(13):8711-22. doi: 10.1074/jbc.M704328200. Epub 2008 Jan 23. J Biol Chem. 2008. PMID: 18216024 Free PMC article.

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