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Protein arginine methyltransferase 5 (PRMT5) inhibition induces lymphoma cell death through reactivation of the retinoblastoma tumor suppressor pathway and polycomb repressor complex 2 (PRC2) silencing.
Chung J, Karkhanis V, Tae S, Yan F, Smith P, Ayers LW, Agostinelli C, Pileri S, Denis GV, Baiocchi RA, Sif S. Chung J, et al. Among authors: smith p. J Biol Chem. 2013 Dec 6;288(49):35534-47. doi: 10.1074/jbc.M113.510669. Epub 2013 Nov 4. J Biol Chem. 2013. PMID: 24189068 Free PMC article.
Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.
Yan F, Alinari L, Lustberg ME, Martin LK, Cordero-Nieves HM, Banasavadi-Siddegowda Y, Virk S, Barnholtz-Sloan J, Bell EH, Wojton J, Jacob NK, Chakravarti A, Nowicki MO, Wu X, Lapalombella R, Datta J, Yu B, Gordon K, Haseley A, Patton JT, Smith PL, Ryu J, Zhang X, Mo X, Marcucci G, Nuovo G, Kwon CH, Byrd JC, Chiocca EA, Li C, Sif S, Jacob S, Lawler S, Kaur B, Baiocchi RA. Yan F, et al. Cancer Res. 2014 Mar 15;74(6):1752-65. doi: 10.1158/0008-5472.CAN-13-0884. Epub 2014 Jan 22. Cancer Res. 2014. PMID: 24453002 Free PMC article.
Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation.
Alinari L, Mahasenan KV, Yan F, Karkhanis V, Chung JH, Smith EM, Quinion C, Smith PL, Kim L, Patton JT, Lapalombella R, Yu B, Wu Y, Roy S, De Leo A, Pileri S, Agostinelli C, Ayers L, Bradner JE, Chen-Kiang S, Elemento O, Motiwala T, Majumder S, Byrd JC, Jacob S, Sif S, Li C, Baiocchi RA. Alinari L, et al. Blood. 2015 Apr 16;125(16):2530-43. doi: 10.1182/blood-2014-12-619783. Epub 2015 Mar 5. Blood. 2015. PMID: 25742700 Free PMC article.
Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
Hing ZA, Walker JS, Whipp EC, Brinton L, Cannon M, Zhang P, Sher S, Cempre CB, Brown F, Smith PL, Agostinelli C, Pileri SA, Skinner JN, Williams K, Phillips H, Shaffer J, Beaver LP, Pan A, Shin K, Gregory CT, Ozer GH, Yilmaz SA, Harrington BK, Lehman AM, Yu L, Coppola V, Yan P, Scherle P, Wang M, Pitis P, Xu C, Vaddi K, Chen-Kiang S, Woyach J, Blachly JS, Alinari L, Yang Y, Byrd JC, Baiocchi RA, Blaser BW, Lapalombella R. Hing ZA, et al. Among authors: smith pl. Nat Commun. 2023 Jan 6;14(1):97. doi: 10.1038/s41467-022-35778-1. Nat Commun. 2023. PMID: 36609611 Free PMC article.
Follicular Helper and Regulatory T Cells Drive the Development of Spontaneous Epstein-Barr Virus Lymphoproliferative Disorder.
Ahmed EH, Lustberg M, Hale C, Sloan S, Mao C, Zhang X, Ozer HG, Schlotter S, Smith PL, Jeney F, Chan WK, Harrington BK, Weigel C, Brooks E, Klimaszewski HL, Oakes CC, Abebe T, Ibrahim ME, Alinari L, Behbehani GK, Shindiapina P, Caligiuri MA, Baiocchi RA. Ahmed EH, et al. Among authors: smith pl. Cancers (Basel). 2023 Jun 3;15(11):3046. doi: 10.3390/cancers15113046. Cancers (Basel). 2023. PMID: 37297008 Free PMC article.
Can artificial intelligence improve patient educational material readability? A systematic review and narrative synthesis.
Nasra M, Jaffri R, Pavlin-Premrl D, Kok HK, Khabaza A, Barras C, Slater LA, Yazdabadi A, Moore J, Russell J, Smith P, Chandra RV, Brooks M, Jhamb A, Chong W, Maingard J, Asadi H. Nasra M, et al. Among authors: smith p. Intern Med J. 2024 Dec 25. doi: 10.1111/imj.16607. Online ahead of print. Intern Med J. 2024. PMID: 39720869 Review.
Outcomes of Debridement, Antibiotics, and Implant Retention in the Management of Infected Total Knee Arthroplasty: Analysis of 5,178 Cases from the National Australian Registry.
Kristensen NK, Callary SA, Nelson R, Harries D, Lorimer M, Smith P, Campbell D. Kristensen NK, et al. Among authors: smith p. J Arthroplasty. 2024 Dec 20:S0883-5403(24)01318-4. doi: 10.1016/j.arth.2024.12.016. Online ahead of print. J Arthroplasty. 2024. PMID: 39710215 Free article.
SARS-CoV-2 infection and COVID-19 outcomes across mental disorders and the role of sex: A register-based study from Catalonia.
Monistrol-Mula A, Giné-Vázquez I, Caggiu G, Conflitti C, Gemes K, Hecker I, Mediavilla R, Monzio Compagnoni M, Pinucci I, Stoffers-Winterling J, Witteveen AB, Smith P, Walter H, Ayuso-Mateos JL, Melchior M, Mittendorfer-Rutz E, Sijbrandij M, Haro JM, Felez-Nobrega M. Monistrol-Mula A, et al. Among authors: smith p. Psychiatry Res. 2024 Dec 12;344:116325. doi: 10.1016/j.psychres.2024.116325. Online ahead of print. Psychiatry Res. 2024. PMID: 39708616 Free article.
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