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Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1.
Reca R, Mastellos D, Majka M, Marquez L, Ratajczak J, Franchini S, Glodek A, Honczarenko M, Spruce LA, Janowska-Wieczorek A, Lambris JD, Ratajczak MZ. Reca R, et al. Among authors: ratajczak j, ratajczak mz. Blood. 2003 May 15;101(10):3784-93. doi: 10.1182/blood-2002-10-3233. Epub 2003 Jan 2. Blood. 2003. PMID: 12511407 Free article.
Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow.
Ratajczak J, Reca R, Kucia M, Majka M, Allendorf DJ, Baran JT, Janowska-Wieczorek A, Wetsel RA, Ross GD, Ratajczak MZ. Ratajczak J, et al. Among authors: ratajczak mz. Blood. 2004 Mar 15;103(6):2071-8. doi: 10.1182/blood-2003-06-2099. Epub 2003 Nov 6. Blood. 2004. PMID: 14604969 Free article.
Both hepatocyte growth factor (HGF) and stromal-derived factor-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radiochemotherapy.
Jankowski K, Kucia M, Wysoczynski M, Reca R, Zhao D, Trzyna E, Trent J, Peiper S, Zembala M, Ratajczak J, Houghton P, Janowska-Wieczorek A, Ratajczak MZ. Jankowski K, et al. Among authors: ratajczak j, ratajczak mz. Cancer Res. 2003 Nov 15;63(22):7926-35. Cancer Res. 2003. PMID: 14633723
536 results