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Page 1
Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules.
Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ. Shaw SY, et al. Among authors: castoreno ab. ACS Chem Biol. 2013 Dec 20;8(12):2724-2733. doi: 10.1021/cb400352d. Epub 2013 Oct 29. ACS Chem Biol. 2013. PMID: 24168452 Free PMC article.
Making the cut: the chemical biology of cytokinesis.
Atilla-Gokcumen GE, Castoreno AB, Sasse S, Eggert US. Atilla-Gokcumen GE, et al. Among authors: castoreno ab. ACS Chem Biol. 2010 Jan 15;5(1):79-90. doi: 10.1021/cb900256m. ACS Chem Biol. 2010. PMID: 20014865 Free PMC article. Review.
Autophagy and the immune system.
Kuballa P, Nolte WM, Castoreno AB, Xavier RJ. Kuballa P, et al. Among authors: castoreno ab. Annu Rev Immunol. 2012;30:611-46. doi: 10.1146/annurev-immunol-020711-074948. Annu Rev Immunol. 2012. PMID: 22449030 Review.
Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection.
Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ. Conway KL, et al. Among authors: castoreno ab. Gastroenterology. 2013 Dec;145(6):1347-57. doi: 10.1053/j.gastro.2013.08.035. Epub 2013 Aug 21. Gastroenterology. 2013. PMID: 23973919 Free PMC article.
Discovery of a Small-Molecule Probe for V-ATPase Function.
Aldrich LN, Kuo SY, Castoreno AB, Goel G, Kuballa P, Rees MG, Seashore-Ludlow BA, Cheah JH, Latorre IJ, Schreiber SL, Shamji AF, Xavier RJ. Aldrich LN, et al. Among authors: castoreno ab. J Am Chem Soc. 2015 Apr 29;137(16):5563-8. doi: 10.1021/jacs.5b02150. Epub 2015 Apr 20. J Am Chem Soc. 2015. PMID: 25860544 Free PMC article.
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.
Kuo SY, Castoreno AB, Aldrich LN, Lassen KG, Goel G, Dančík V, Kuballa P, Latorre I, Conway KL, Sarkar S, Maetzel D, Jaenisch R, Clemons PA, Schreiber SL, Shamji AF, Xavier RJ. Kuo SY, et al. Among authors: castoreno ab. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4281-7. doi: 10.1073/pnas.1512289112. Epub 2015 Jul 20. Proc Natl Acad Sci U S A. 2015. PMID: 26195741 Free PMC article.
28 results