Ludbrook S - Search Results

1

Preclinical SPECT/CT imaging of αvβ6 integrins for molecular stratification of idiopathic pulmonary fibrosis.

John AE, Luckett JC, Tatler AL, Awais RO, Desai A, Habgood A, Ludbrook S, Blanchard AD, Perkins AC, Jenkins RG, Marshall JF. John AE, et al. Among authors: ludbrook s. J Nucl Med. 2013 Dec;54(12):2146-52. doi: 10.2967/jnumed.113.120592. Epub 2013 Oct 28. J Nucl Med. 2013. PMID: 24167080 Free article.

2

Pharmacological Characterization of the αvβ6 Integrin Binding and Internalization Kinetics of the Foot-and-Mouth Disease Virus Derived Peptide A20FMDV2.

Slack RJ, Hafeji M, Rogers R, Ludbrook SB, Marshall JF, Flint DJ, Pyne S, Denyer JC. Slack RJ, et al. Among authors: ludbrook sb. Pharmacology. 2016;97(3-4):114-25. doi: 10.1159/000443180. Epub 2016 Jan 7. Pharmacology. 2016. PMID: 26734728 Free article.

3

A phenotypic screening approach in cord blood-derived mast cells to identify anti-inflammatory compounds.

Kaur R, Sloan LA, Blanchard AD, Smith JL, Churcher I, Wayne GJ, Ludbrook SB. Kaur R, et al. Among authors: ludbrook sb. J Biomol Screen. 2013 Dec;18(10):1223-33. doi: 10.1177/1087057113500073. Epub 2013 Aug 27. J Biomol Screen. 2013. PMID: 23983232

4

Determining the True Selectivity Profile of αv Integrin Ligands Using Radioligand Binding: Applying an Old Solution to a New Problem.

Rowedder JE, Ludbrook SB, Slack RJ. Rowedder JE, et al. Among authors: ludbrook sb. SLAS Discov. 2017 Sep;22(8):962-973. doi: 10.1177/2472555217703908. Epub 2017 Apr 17. SLAS Discov. 2017. PMID: 28414923 Free article.

5

An αv-RGD Integrin Inhibitor Toolbox: Drug Discovery Insight, Challenges and Opportunities.

Hatley RJD, Macdonald SJF, Slack RJ, Le J, Ludbrook SB, Lukey PT. Hatley RJD, et al. Among authors: ludbrook sb. Angew Chem Int Ed Engl. 2018 Mar 19;57(13):3298-3321. doi: 10.1002/anie.201707948. Epub 2018 Feb 21. Angew Chem Int Ed Engl. 2018. PMID: 28944552 Review.

6

Analysis of the alpha4beta1 integrin-osteopontin interaction.

Barry ST, Ludbrook SB, Murrison E, Horgan CM. Barry ST, et al. Among authors: ludbrook sb. Exp Cell Res. 2000 Aug 1;258(2):342-51. doi: 10.1006/excr.2000.4941. Exp Cell Res. 2000. PMID: 10896785

7

The integrin alphavbeta3 is a receptor for the latency-associated peptides of transforming growth factors beta1 and beta3.

Ludbrook SB, Barry ST, Delves CJ, Horgan CM. Ludbrook SB, et al. Biochem J. 2003 Jan 15;369(Pt 2):311-8. doi: 10.1042/BJ20020809. Biochem J. 2003. PMID: 12358597 Free PMC article.

8

Structural elements of the osteopontin SVVYGLR motif important for the interaction with alpha(4) integrins.

Green PM, Ludbrook SB, Miller DD, Horgan CM, Barry ST. Green PM, et al. Among authors: ludbrook sb. FEBS Lett. 2001 Aug 10;503(1):75-9. doi: 10.1016/s0014-5793(01)02690-4. FEBS Lett. 2001. PMID: 11513858 Free article.

9

Mathematical Modeling of Complement Pathway Dynamics for Target Validation and Selection of Drug Modalities for Complement Therapies.

Bansal L, Nichols EM, Howsmon DP, Neisen J, Bessant CM, Cunningham F, Petit-Frere S, Ludbrook S, Damian V. Bansal L, et al. Among authors: ludbrook s. Front Pharmacol. 2022 Apr 19;13:855743. doi: 10.3389/fphar.2022.855743. eCollection 2022. Front Pharmacol. 2022. PMID: 35517827 Free PMC article.

10

Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes.

Angell RM, Angell TD, Bamborough P, Bamford MJ, Chung CW, Cockerill SG, Flack SS, Jones KL, Laine DI, Longstaff T, Ludbrook S, Pearson R, Smith KJ, Smee PA, Somers DO, Walker AL. Angell RM, et al. Among authors: ludbrook s. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4433-7. doi: 10.1016/j.bmcl.2008.06.028. Epub 2008 Jun 12. Bioorg Med Chem Lett. 2008. PMID: 18602262

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