Fröhlich RF - Search Results

1

Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases.

Zhang Y, Evans GB, Clinch K, Crump DR, Harris LD, Fröhlich RF, Tyler PC, Hazleton KZ, Cassera MB, Schramm VL. Zhang Y, et al. Among authors: frohlich rf. J Biol Chem. 2013 Nov 29;288(48):34746-54. doi: 10.1074/jbc.M113.521955. Epub 2013 Oct 24. J Biol Chem. 2013. PMID: 24158442 Free PMC article.

2

Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1.

Riegelhaupt PM, Cassera MB, Fröhlich RF, Hazleton KZ, Hefter JJ, Schramm VL, Akabas MH. Riegelhaupt PM, et al. Among authors: frohlich rf. Mol Biochem Parasitol. 2010 Jan;169(1):40-9. doi: 10.1016/j.molbiopara.2009.10.001. Epub 2009 Oct 8. Mol Biochem Parasitol. 2010. PMID: 19818813 Free PMC article.

3

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.

Clinch K, Evans GB, Fröhlich RF, Furneaux RH, Kelly PM, Legentil L, Murkin AS, Li L, Schramm VL, Tyler PC, Woolhouse AD. Clinch K, et al. Among authors: frohlich rf. J Med Chem. 2009 Feb 26;52(4):1126-43. doi: 10.1021/jm801421q. J Med Chem. 2009. PMID: 19170524 Free PMC article.

4

Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.

Clinch K, Evans GB, Fröhlich RF, Gulab SA, Gutierrez JA, Mason JM, Schramm VL, Tyler PC, Woolhouse AD. Clinch K, et al. Among authors: frohlich rf. Bioorg Med Chem. 2012 Sep 1;20(17):5181-7. doi: 10.1016/j.bmc.2012.07.006. Epub 2012 Jul 14. Bioorg Med Chem. 2012. PMID: 22854195 Free PMC article.

5

Methylthioadenosine deaminase in an alternative quorum sensing pathway in Pseudomonas aeruginosa.

Guan R, Ho MC, Fröhlich RF, Tyler PC, Almo SC, Schramm VL. Guan R, et al. Among authors: frohlich rf. Biochemistry. 2012 Nov 13;51(45):9094-103. doi: 10.1021/bi301062y. Epub 2012 Nov 2. Biochemistry. 2012. PMID: 23050701 Free PMC article.

6

Aminofutalosine Deaminase in the Menaquinone Pathway of Helicobacter pylori.

Feng M, Harijan RK, Harris LD, Tyler PC, Fröhlich RFG, Brown M, Schramm VL. Feng M, et al. Among authors: frohlich rfg. Biochemistry. 2021 Jun 22;60(24):1933-1946. doi: 10.1021/acs.biochem.1c00215. Epub 2021 Jun 2. Biochemistry. 2021. PMID: 34077175 Free PMC article.

7

Synthesis of 5'-methylthio coformycins: specific inhibitors for malarial adenosine deaminase.

Tyler PC, Taylor EA, Fröhlich RF, Schramm VL. Tyler PC, et al. Among authors: frohlich rf. J Am Chem Soc. 2007 May 30;129(21):6872-9. doi: 10.1021/ja0708363. Epub 2007 May 8. J Am Chem Soc. 2007. PMID: 17488013 Free PMC article.

8

7-(5-Methyl-sulfanyl-β-d-erythrofuran-osyl)-7H-pyrrolo-[2,3-d]pyrimidin-4-amine monohydrate (MT-tubercidin·H(2)O).

Gainsford GJ, Fröhlich RF, Evans GB. Gainsford GJ, et al. Among authors: frohlich rf. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 18;66(Pt 7):o1688-9. doi: 10.1107/S1600536810020179. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21587912 Free PMC article.

9

A fluorescent probe for GM1 gangliosidosis related β-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol.

Fröhlich RF, Fantur K, Furneaux RH, Paschke E, Stütz AE, Wicki J, Withers SG, Wrodnigg TM. Fröhlich RF, et al. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6872-5. doi: 10.1016/j.bmcl.2011.09.012. Epub 2011 Sep 10. Bioorg Med Chem Lett. 2011. PMID: 21974950

10

1-Deoxynojirimycins with dansyl capped N-substituents as probes for Morbus Gaucher affected cell lines.

Fröhlich RF, Furneaux RH, Mahuran DJ, Rigat BA, Stütz AE, Tropak MB, Wicki J, Withers SG, Wrodnigg TM. Fröhlich RF, et al. Carbohydr Res. 2010 Jul 2;345(10):1371-6. doi: 10.1016/j.carres.2010.04.015. Epub 2010 Apr 24. Carbohydr Res. 2010. PMID: 20471633 Free PMC article.

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