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A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours.
Horsley L, Cummings J, Middleton M, Ward T, Backen A, Clamp A, Dawson M, Farmer H, Fisher N, Halbert G, Halford S, Harris A, Hasan J, Hogg P, Kumaran G, Little R, Parker GJ, Potter P, Saunders M, Roberts C, Shaw D, Smith N, Smythe J, Taylor A, Turner H, Watson Y, Dive C, Jayson GC; Cancer Research UK Drug Development Office Phase I clinical trial. Horsley L, et al. Among authors: smith n. Cancer Chemother Pharmacol. 2013 Dec;72(6):1343-52. doi: 10.1007/s00280-013-2320-9. Epub 2013 Oct 20. Cancer Chemother Pharmacol. 2013. PMID: 24141375 Clinical Trial.
Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: implications for trial design of antiangiogenic antibodies.
Jayson GC, Zweit J, Jackson A, Mulatero C, Julyan P, Ranson M, Broughton L, Wagstaff J, Hakannson L, Groenewegen G, Bailey J, Smith N, Hastings D, Lawrance J, Haroon H, Ward T, McGown AT, Tang M, Levitt D, Marreaud S, Lehmann FF, Herold M, Zwierzina H; European Organisation for Research and Treatment of Cancer Biological Therapeutic Development Group. Jayson GC, et al. Among authors: smith n. J Natl Cancer Inst. 2002 Oct 2;94(19):1484-93. doi: 10.1093/jnci/94.19.1484. J Natl Cancer Inst. 2002. PMID: 12359857 Clinical Trial.
Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample.
Rothwell DG, Smith N, Morris D, Leong HS, Li Y, Hollebecque A, Ayub M, Carter L, Antonello J, Franklin L, Miller C, Blackhall F, Dive C, Brady G. Rothwell DG, et al. Among authors: smith n. Mol Oncol. 2016 Apr;10(4):566-74. doi: 10.1016/j.molonc.2015.11.006. Epub 2015 Nov 19. Mol Oncol. 2016. PMID: 26639657 Free PMC article.
Development of a circulating miRNA assay to monitor tumor burden: From mouse to man.
Greystoke A, Ayub M, Rothwell DG, Morris D, Burt D, Hodgkinson CL, Morrow CJ, Smith N, Aung K, Valle J, Carter L, Blackhall F, Dive C, Brady G. Greystoke A, et al. Among authors: smith n. Mol Oncol. 2016 Feb;10(2):282-91. doi: 10.1016/j.molonc.2015.10.004. Epub 2015 Oct 28. Mol Oncol. 2016. PMID: 26654130 Free PMC article.
Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study.
Rothwell DG, Ayub M, Cook N, Thistlethwaite F, Carter L, Dean E, Smith N, Villa S, Dransfield J, Clipson A, White D, Nessa K, Ferdous S, Howell M, Gupta A, Kilerci B, Mohan S, Frese K, Gulati S, Miller C, Jordan A, Eaton H, Hickson N, O'Brien C, Graham D, Kelly C, Aruketty S, Metcalf R, Chiramel J, Tinsley N, Vickers AJ, Kurup R, Frost H, Stevenson J, Southam S, Landers D, Wallace A, Marais R, Hughes AM, Brady G, Dive C, Krebs MG. Rothwell DG, et al. Among authors: smith n. Nat Med. 2019 May;25(5):738-743. doi: 10.1038/s41591-019-0380-z. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011204 Free article.
5,959 results