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A phase 1 trial of intravenous 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO) in patients with advanced solid tumours.
Horsley L, Cummings J, Middleton M, Ward T, Backen A, Clamp A, Dawson M, Farmer H, Fisher N, Halbert G, Halford S, Harris A, Hasan J, Hogg P, Kumaran G, Little R, Parker GJ, Potter P, Saunders M, Roberts C, Shaw D, Smith N, Smythe J, Taylor A, Turner H, Watson Y, Dive C, Jayson GC; Cancer Research UK Drug Development Office Phase I clinical trial. Horsley L, et al. Among authors: dive c. Cancer Chemother Pharmacol. 2013 Dec;72(6):1343-52. doi: 10.1007/s00280-013-2320-9. Epub 2013 Oct 20. Cancer Chemother Pharmacol. 2013. PMID: 24141375 Clinical Trial.
Method validation and preliminary qualification of pharmacodynamic biomarkers employed to evaluate the clinical efficacy of an antisense compound (AEG35156) targeted to the X-linked inhibitor of apoptosis protein XIAP.
Cummings J, Ranson M, Lacasse E, Ganganagari JR, St-Jean M, Jayson G, Durkin J, Dive C. Cummings J, et al. Among authors: dive c. Br J Cancer. 2006 Jul 3;95(1):42-8. doi: 10.1038/sj.bjc.6603220. Br J Cancer. 2006. PMID: 16804528 Free PMC article.
Biomarker method validation in anticancer drug development.
Cummings J, Ward TH, Greystoke A, Ranson M, Dive C. Cummings J, et al. Among authors: dive c. Br J Pharmacol. 2008 Feb;153(4):646-56. doi: 10.1038/sj.bjp.0707441. Epub 2007 Sep 17. Br J Pharmacol. 2008. PMID: 17876307 Free PMC article. Review.
Optimisation of circulating biomarkers of cell death for routine clinical use.
Greystoke A, Cummings J, Ward T, Simpson K, Renehan A, Butt F, Moore D, Gietema J, Blackhall F, Ranson M, Hughes A, Dive C. Greystoke A, et al. Among authors: dive c. Ann Oncol. 2008 May;19(5):990-5. doi: 10.1093/annonc/mdn014. Epub 2008 Feb 27. Ann Oncol. 2008. PMID: 18304966 Free article.
Quantitative multiplexed quantum dot immunohistochemistry.
Sweeney E, Ward TH, Gray N, Womack C, Jayson G, Hughes A, Dive C, Byers R. Sweeney E, et al. Among authors: dive c. Biochem Biophys Res Commun. 2008 Sep 19;374(2):181-6. doi: 10.1016/j.bbrc.2008.06.127. Epub 2008 Jul 11. Biochem Biophys Res Commun. 2008. PMID: 18621021
437 results