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An adenosine nucleoside inhibitor of dengue virus.
Yin Z, Chen YL, Schul W, Wang QY, Gu F, Duraiswamy J, Kondreddi RR, Niyomrattanakit P, Lakshminarayana SB, Goh A, Xu HY, Liu W, Liu B, Lim JY, Ng CY, Qing M, Lim CC, Yip A, Wang G, Chan WL, Tan HP, Lin K, Zhang B, Zou G, Bernard KA, Garrett C, Beltz K, Dong M, Weaver M, He H, Pichota A, Dartois V, Keller TH, Shi PY. Yin Z, et al. Among authors: chen yl. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20435-9. doi: 10.1073/pnas.0907010106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918064 Free PMC article.
N-sulfonylanthranilic acid derivatives as allosteric inhibitors of dengue viral RNA-dependent RNA polymerase.
Yin Z, Chen YL, Kondreddi RR, Chan WL, Wang G, Ng RH, Lim JY, Lee WY, Jeyaraj DA, Niyomrattanakit P, Wen D, Chao A, Glickman JF, Voshol H, Mueller D, Spanka C, Dressler S, Nilar S, Vasudevan SG, Shi PY, Keller TH. Yin Z, et al. Among authors: chen yl. J Med Chem. 2009 Dec 24;52(24):7934-7. doi: 10.1021/jm901044z. J Med Chem. 2009. PMID: 20014868
Strategies for development of Dengue virus inhibitors.
Noble CG, Chen YL, Dong H, Gu F, Lim SP, Schul W, Wang QY, Shi PY. Noble CG, et al. Among authors: chen yl. Antiviral Res. 2010 Mar;85(3):450-62. doi: 10.1016/j.antiviral.2009.12.011. Epub 2010 Jan 8. Antiviral Res. 2010. PMID: 20060421 Review.
Inhibition of dengue virus polymerase by blocking of the RNA tunnel.
Niyomrattanakit P, Chen YL, Dong H, Yin Z, Qing M, Glickman JF, Lin K, Mueller D, Voshol H, Lim JY, Nilar S, Keller TH, Shi PY. Niyomrattanakit P, et al. Among authors: chen yl. J Virol. 2010 Jun;84(11):5678-86. doi: 10.1128/JVI.02451-09. Epub 2010 Mar 17. J Virol. 2010. PMID: 20237086 Free PMC article.
Inhibition of dengue virus RNA synthesis by an adenosine nucleoside.
Chen YL, Yin Z, Duraiswamy J, Schul W, Lim CC, Liu B, Xu HY, Qing M, Yip A, Wang G, Chan WL, Tan HP, Lo M, Liung S, Kondreddi RR, Rao R, Gu H, He H, Keller TH, Shi PY. Chen YL, et al. Antimicrob Agents Chemother. 2010 Jul;54(7):2932-9. doi: 10.1128/AAC.00140-10. Epub 2010 May 10. Antimicrob Agents Chemother. 2010. PMID: 20457821 Free PMC article.
Inhibition of dengue virus by an ester prodrug of an adenosine analog.
Chen YL, Yin Z, Lakshminarayana SB, Qing M, Schul W, Duraiswamy J, Kondreddi RR, Goh A, Xu HY, Yip A, Liu B, Weaver M, Dartois V, Keller TH, Shi PY. Chen YL, et al. Antimicrob Agents Chemother. 2010 Aug;54(8):3255-61. doi: 10.1128/AAC.00397-10. Epub 2010 Jun 1. Antimicrob Agents Chemother. 2010. PMID: 20516277 Free PMC article.
Functional analysis of two cavities in flavivirus NS5 polymerase.
Zou G, Chen YL, Dong H, Lim CC, Yap LJ, Yau YH, Shochat SG, Lescar J, Shi PY. Zou G, et al. Among authors: chen yl. J Biol Chem. 2011 Apr 22;286(16):14362-72. doi: 10.1074/jbc.M110.214189. Epub 2011 Feb 23. J Biol Chem. 2011. PMID: 21349834 Free PMC article.
4,473 results