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Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.
He J, Tsai LM, Leong YA, Hu X, Ma CS, Chevalier N, Sun X, Vandenberg K, Rockman S, Ding Y, Zhu L, Wei W, Wang C, Karnowski A, Belz GT, Ghali JR, Cook MC, Riminton DS, Veillette A, Schwartzberg PL, Mackay F, Brink R, Tangye SG, Vinuesa CG, Mackay CR, Li Z, Yu D. He J, et al. Among authors: tsai lm. Immunity. 2013 Oct 17;39(4):770-81. doi: 10.1016/j.immuni.2013.09.007. Immunity. 2013. PMID: 24138884 Free article.
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.
Yu D, Rao S, Tsai LM, Lee SK, He Y, Sutcliffe EL, Srivastava M, Linterman M, Zheng L, Simpson N, Ellyard JI, Parish IA, Ma CS, Li QJ, Parish CR, Mackay CR, Vinuesa CG. Yu D, et al. Among authors: tsai lm. Immunity. 2009 Sep 18;31(3):457-68. doi: 10.1016/j.immuni.2009.07.002. Epub 2009 Jul 23. Immunity. 2009. PMID: 19631565 Free article.
B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells.
Lee SK, Rigby RJ, Zotos D, Tsai LM, Kawamoto S, Marshall JL, Ramiscal RR, Chan TD, Gatto D, Brink R, Yu D, Fagarasan S, Tarlinton DM, Cunningham AF, Vinuesa CG. Lee SK, et al. Among authors: tsai lm. J Exp Med. 2011 Jul 4;208(7):1377-88. doi: 10.1084/jem.20102065. Epub 2011 Jun 27. J Exp Med. 2011. PMID: 21708925 Free PMC article.
175 results