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The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG.
Valdeolivas S, Pazos MR, Bisogno T, Piscitelli F, Iannotti FA, Allarà M, Sagredo O, Di Marzo V, Fernández-Ruiz J. Valdeolivas S, et al. Cell Death Dis. 2013 Oct 17;4(10):e862. doi: 10.1038/cddis.2013.387. Cell Death Dis. 2013. PMID: 24136226 Free PMC article.
A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington's disease.
López-Sendón Moreno JL, García Caldentey J, Trigo Cubillo P, Ruiz Romero C, García Ribas G, Alonso Arias MA, García de Yébenes MJ, Tolón RM, Galve-Roperh I, Sagredo O, Valdeolivas S, Resel E, Ortega-Gutierrez S, García-Bermejo ML, Fernández Ruiz J, Guzmán M, García de Yébenes Prous J. López-Sendón Moreno JL, et al. Among authors: valdeolivas s. J Neurol. 2016 Jul;263(7):1390-400. doi: 10.1007/s00415-016-8145-9. Epub 2016 May 9. J Neurol. 2016. PMID: 27159993 Clinical Trial.
Prospects for cannabinoid therapies in basal ganglia disorders.
Fernández-Ruiz J, Moreno-Martet M, Rodríguez-Cueto C, Palomo-Garo C, Gómez-Cañas M, Valdeolivas S, Guaza C, Romero J, Guzmán M, Mechoulam R, Ramos JA. Fernández-Ruiz J, et al. Among authors: valdeolivas s. Br J Pharmacol. 2011 Aug;163(7):1365-78. doi: 10.1111/j.1476-5381.2011.01365.x. Br J Pharmacol. 2011. PMID: 21545415 Free PMC article. Review.
Dysregulation of the endocannabinoid signaling system in the cerebellum and brainstem in a transgenic mouse model of spinocerebellar ataxia type-3.
Rodríguez-Cueto C, Hernández-Gálvez M, Hillard CJ, Maciel P, García-García L, Valdeolivas S, Pozo MA, Ramos JA, Gómez-Ruiz M, Fernández-Ruiz J. Rodríguez-Cueto C, et al. Among authors: valdeolivas s. Neuroscience. 2016 Dec 17;339:191-209. doi: 10.1016/j.neuroscience.2016.09.046. Epub 2016 Oct 4. Neuroscience. 2016. PMID: 27717809
11 results